埃塞俄比亚西北部费利格·希沃特综合专科医院糖尿病患者的药物相关负担及相关因素

Frontiers in clinical diabetes and healthcare Pub Date : 2022-09-09 eCollection Date: 2022-01-01 DOI:10.3389/fcdhc.2022.977216
Abaynesh Fentahun Bekalu, Melaku Kindie Yenit, Masho Tigabe Tekile, Mequanent Kassa Birarra
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引用次数: 0

摘要

背景:从患者的角度评估药物负担对于获得糖尿病(DM)管理的良好健康结果至关重要。然而,有关这一敏感领域的数据有限。因此,本研究旨在确定埃塞俄比亚西北部Felege Hiwot综合专科医院(FHCSH)糖尿病患者的药物相关负担(MRB)及其相关因素。药物相关负担通过使用药物生活问卷第3版(LMQ-3)进行测量。多元线性回归用于确定与药物相关负担相关的因素,并以95%置信区间(CI)报告。p值结果:LMQ-3平均得分为126.52(±17.39)。大多数参与者经历了中度(58.9%,95%CI:53.9-63.7)至高度(26.2%,95%CI:22.5-30.0)的药物负担。近一半(44.9%,95%置信区间:39.9-49.7)的参与者对处方药不依从。VAS评分(B=12.773,p=0.001)、ARMS评分(B=8.505,p=0.001)和访视时空腹血糖(FBS)(B=5.858,p=0.003)与高药物相关负担显著相关。结论:相当多的患者存在与药物相关的高负担和不坚持长期服药的问题。因此,需要多层面干预来降低MRB并提高依从性,以提高患者的生活质量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Medication-related burden and associated factors among diabetes mellitus patients at Felege Hiwot Comprehensive Specialized Hospital in northwest Ethiopia.

Medication-related burden and associated factors among diabetes mellitus patients at Felege Hiwot Comprehensive Specialized Hospital in northwest Ethiopia.

Background: Evaluating the medicine burden from the patients' perspective is essential for getting good health outcomes of diabetes mellitus (DM) management. However, data are limited regarding this sensitive area. Thus, the study was aimed to determine the medication-related burden (MRB) and associated factors among DM patients at Felege Hiwot Comprehensive Specialized Hospital (FHCSH) in northwest Ethiopia.

Methods: A cross-sectional study was conducted on 423 systematically selected DM patients attending the DM clinic of FHCSH from June to August 2020. The medication-related burden was measured by using the Living with Medicines Questionnaire version 3 (LMQ-3). Multiple linear regression was used to identify factors associated with medication-related burden and reported with 95% confidence interval (CI). p-value <0.05 was considered as statistically significant to declare an association.

Results: The mean LMQ-3 score was 126.52 ( ± 17.39). The majority of the participants experienced moderate (58.9%, 95% CI: 53.9-63.7) to high (26.2%, 95% CI: 22.5-30.0) degrees of medication burden. Nearly half (44.9%, 95% CI: 39.9-49.7) of the participants were non-adherent to their prescribed medications. VAS score (B = 12.773, p = 0.001), ARMS score (B = 8.505, p = 0.001), and fasting blood glucose (FBS) on visit (B = 5.858, p = 0.003) were significantly associated with high medication-related burden.

Conclusion: A significant number of patients suffered from high medication-related burden and non-adherence to long-term medicine. Therefore, multidimensional intervention to decrease MRB and to upgrade adherence is required to increase patients' quality of life.

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