Talita Thomaz Nader, Alexandre Henrique Leonel, Camila Yamasita Henrique, Silvia Helena Taleb Contini, Eduardo José Crevelin, Suzelei de Castro França, Bianca Waléria Berton, Ana Maria Soares Pereira
{"title":"动态水杨花(Griseb)精油:一种很有前途的抗菌产品。","authors":"Talita Thomaz Nader, Alexandre Henrique Leonel, Camila Yamasita Henrique, Silvia Helena Taleb Contini, Eduardo José Crevelin, Suzelei de Castro França, Bianca Waléria Berton, Ana Maria Soares Pereira","doi":"10.1055/s-0042-1748320","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Compounds from vegetal matter have therapeutic potential to control highly prevalent microorganisms that are resistant to commonly used antimicrobial drugs. Dynamization of compounds can either maintain or improve their therapeutic effects, and make their use safer, especially those compounds whose therapeutic dose is close to the toxic limit. <i>Aloysia polystachya</i> (Griseb.) stands out among aromatic plants with antimicrobial potential.</p><p><strong>Objective: </strong>The aim of this study was to evaluate the antimicrobial activity of dynamized and crude forms of <i>A. polystachya</i> essential oil against <i>Candida albicans</i>, <i>Escherichia coli</i> and <i>Staphylococcus aureus</i>.</p><p><strong>Methods: </strong>Essential oil was extracted from <i>A. polystachya</i> dry leaves, solubilized, and dynamized at 1 cH potency as recommended by the Brazilian Homeopathic Pharmacopoeia. Antimicrobial activity against <i>C. albicans</i>, <i>E. coli</i> and <i>S. aureus</i> of the samples was assayed using the plate microdilution method.</p><p><strong>Results: </strong>Dynamized <i>A. polystachya</i> essential oil at the concentration of 1 μg/mL inhibited the growth of all the microbial species analyzed. The minimum inhibitory concentration of dynamized essential oil was smaller than crude essential oil for <i>S. aureus</i>, <i>E. coli</i> and <i>C. albicans</i>.</p><p><strong>Conclusion: </strong>It is reported for the first time that <i>A. polystachya</i> dynamized essential oil can effectively suppress microbial growth, and it is a promising adjuvant to treat infections with pathogenic <i>S. aureus</i>, <i>E. coli</i> and <i>C. albicans</i>.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":"112 2","pages":"120-124"},"PeriodicalIF":1.2000,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Dynamized Aloysia Polystachya (Griseb.) Essential Oil: A Promising Antimicrobial Product.\",\"authors\":\"Talita Thomaz Nader, Alexandre Henrique Leonel, Camila Yamasita Henrique, Silvia Helena Taleb Contini, Eduardo José Crevelin, Suzelei de Castro França, Bianca Waléria Berton, Ana Maria Soares Pereira\",\"doi\":\"10.1055/s-0042-1748320\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Compounds from vegetal matter have therapeutic potential to control highly prevalent microorganisms that are resistant to commonly used antimicrobial drugs. Dynamization of compounds can either maintain or improve their therapeutic effects, and make their use safer, especially those compounds whose therapeutic dose is close to the toxic limit. <i>Aloysia polystachya</i> (Griseb.) stands out among aromatic plants with antimicrobial potential.</p><p><strong>Objective: </strong>The aim of this study was to evaluate the antimicrobial activity of dynamized and crude forms of <i>A. polystachya</i> essential oil against <i>Candida albicans</i>, <i>Escherichia coli</i> and <i>Staphylococcus aureus</i>.</p><p><strong>Methods: </strong>Essential oil was extracted from <i>A. polystachya</i> dry leaves, solubilized, and dynamized at 1 cH potency as recommended by the Brazilian Homeopathic Pharmacopoeia. Antimicrobial activity against <i>C. albicans</i>, <i>E. coli</i> and <i>S. aureus</i> of the samples was assayed using the plate microdilution method.</p><p><strong>Results: </strong>Dynamized <i>A. polystachya</i> essential oil at the concentration of 1 μg/mL inhibited the growth of all the microbial species analyzed. The minimum inhibitory concentration of dynamized essential oil was smaller than crude essential oil for <i>S. aureus</i>, <i>E. coli</i> and <i>C. albicans</i>.</p><p><strong>Conclusion: </strong>It is reported for the first time that <i>A. polystachya</i> dynamized essential oil can effectively suppress microbial growth, and it is a promising adjuvant to treat infections with pathogenic <i>S. aureus</i>, <i>E. coli</i> and <i>C. albicans</i>.</p>\",\"PeriodicalId\":13227,\"journal\":{\"name\":\"Homeopathy\",\"volume\":\"112 2\",\"pages\":\"120-124\"},\"PeriodicalIF\":1.2000,\"publicationDate\":\"2023-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Homeopathy\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1055/s-0042-1748320\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"INTEGRATIVE & COMPLEMENTARY MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Homeopathy","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1055/s-0042-1748320","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"INTEGRATIVE & COMPLEMENTARY MEDICINE","Score":null,"Total":0}
Dynamized Aloysia Polystachya (Griseb.) Essential Oil: A Promising Antimicrobial Product.
Background: Compounds from vegetal matter have therapeutic potential to control highly prevalent microorganisms that are resistant to commonly used antimicrobial drugs. Dynamization of compounds can either maintain or improve their therapeutic effects, and make their use safer, especially those compounds whose therapeutic dose is close to the toxic limit. Aloysia polystachya (Griseb.) stands out among aromatic plants with antimicrobial potential.
Objective: The aim of this study was to evaluate the antimicrobial activity of dynamized and crude forms of A. polystachya essential oil against Candida albicans, Escherichia coli and Staphylococcus aureus.
Methods: Essential oil was extracted from A. polystachya dry leaves, solubilized, and dynamized at 1 cH potency as recommended by the Brazilian Homeopathic Pharmacopoeia. Antimicrobial activity against C. albicans, E. coli and S. aureus of the samples was assayed using the plate microdilution method.
Results: Dynamized A. polystachya essential oil at the concentration of 1 μg/mL inhibited the growth of all the microbial species analyzed. The minimum inhibitory concentration of dynamized essential oil was smaller than crude essential oil for S. aureus, E. coli and C. albicans.
Conclusion: It is reported for the first time that A. polystachya dynamized essential oil can effectively suppress microbial growth, and it is a promising adjuvant to treat infections with pathogenic S. aureus, E. coli and C. albicans.
期刊介绍：
Homeopathy is an international peer-reviewed journal aimed at improving the fundamental understanding and clinical practice of homeopathy by publishing relevant high-quality original research articles, reviews, and case reports. It also promotes commentary and debate on matters of topical interest in homeopathy.
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