{"title":"两栖动物线虫寄生虫（Aplectana chamaeleonis）的首次基因组组装。","authors":"Lei Han, Tianlu Liu, Fengping He, Zhijun Hou","doi":"10.46471/gigabyte.79","DOIUrl":null,"url":null,"abstract":"<p><p>Cosmocercoid nematodes are common parasites of the digestive tract of amphibians. Genomic resources are important for understanding the evolution of a species and the molecular mechanisms of parasite adaptation. So far, no genome resource of Cosmocercoid has been reported. In 2020, a massive Cosmocercoid infection was found in the small intestine of a toad, causing severe intestinal blockage. We morphologically identified this parasite as <i>A. chamaeleonis</i>. Here, we report the first <i>A. chamaeleonis</i> genome with a genome size of 1.04 Gb. The repeat content of this <i>A. chamaeleonis</i> genome is 72.45%, and the total length is 751 Mb. This resource is fundamental for understanding the evolution of Cosmocercoid and provides the molecular basis for Cosmocercoid infection and control.</p>","PeriodicalId":73157,"journal":{"name":"GigaByte (Hong Kong, China)","volume":"2023 ","pages":"gigabyte79"},"PeriodicalIF":0.0000,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043924/pdf/","citationCount":"0","resultStr":"{\"title\":\"The first genome assembly of the amphibian nematode parasite (<i>Aplectana chamaeleonis</i>).\",\"authors\":\"Lei Han, Tianlu Liu, Fengping He, Zhijun Hou\",\"doi\":\"10.46471/gigabyte.79\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Cosmocercoid nematodes are common parasites of the digestive tract of amphibians. Genomic resources are important for understanding the evolution of a species and the molecular mechanisms of parasite adaptation. So far, no genome resource of Cosmocercoid has been reported. In 2020, a massive Cosmocercoid infection was found in the small intestine of a toad, causing severe intestinal blockage. We morphologically identified this parasite as <i>A. chamaeleonis</i>. Here, we report the first <i>A. chamaeleonis</i> genome with a genome size of 1.04 Gb. The repeat content of this <i>A. chamaeleonis</i> genome is 72.45%, and the total length is 751 Mb. This resource is fundamental for understanding the evolution of Cosmocercoid and provides the molecular basis for Cosmocercoid infection and control.</p>\",\"PeriodicalId\":73157,\"journal\":{\"name\":\"GigaByte (Hong Kong, China)\",\"volume\":\"2023 \",\"pages\":\"gigabyte79\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-03-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043924/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"GigaByte (Hong Kong, China)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.46471/gigabyte.79\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2023/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"GigaByte (Hong Kong, China)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.46471/gigabyte.79","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
Cosmocercoid 线虫是两栖动物消化道的常见寄生虫。基因组资源对于了解一个物种的进化和寄生虫适应的分子机制非常重要。迄今为止，还没有关于 Cosmocercoid 的基因组资源的报道。2020 年，在一只蟾蜍的小肠中发现了大量的 Cosmocercoid 感染，造成了严重的肠道堵塞。我们从形态学上确定这种寄生虫为 A. chamaeleonis。在此，我们报告了第一个 A. chamaeleonis 基因组，其基因组大小为 1.04 Gb。该 A. chamaeleonis 基因组的重复率为 72.45%，总长度为 751 Mb。这一资源对于了解 Cosmocercoid 的进化至关重要，并为 Cosmocercoid 的感染和控制提供了分子基础。
The first genome assembly of the amphibian nematode parasite (Aplectana chamaeleonis).
Cosmocercoid nematodes are common parasites of the digestive tract of amphibians. Genomic resources are important for understanding the evolution of a species and the molecular mechanisms of parasite adaptation. So far, no genome resource of Cosmocercoid has been reported. In 2020, a massive Cosmocercoid infection was found in the small intestine of a toad, causing severe intestinal blockage. We morphologically identified this parasite as A. chamaeleonis. Here, we report the first A. chamaeleonis genome with a genome size of 1.04 Gb. The repeat content of this A. chamaeleonis genome is 72.45%, and the total length is 751 Mb. This resource is fundamental for understanding the evolution of Cosmocercoid and provides the molecular basis for Cosmocercoid infection and control.
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