2017-2022年马萨诸塞州总医院职业和接触性皮炎诊所的补丁测试结果。

IF 4 3区医学 Q1 DERMATOLOGY

Dermatitis Pub Date : 2023-11-01 Epub Date: 2023-05-24 DOI:10.1089/derm.2023.0085

Hadley Johnson, JiaDe Yu

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引用次数: 0

摘要

背景:斑贴试验是鉴别过敏性接触性皮炎(ACD)来源的金标准。目的:报告美国马萨诸塞州总医院(MGH)职业与接触性皮炎门诊2017 - 2022年的斑贴试验结果。方法:回顾性分析2017-2022年在MGH进行贴片试验的患者。结果:共纳入1438例患者。1168例(81.2%)患者出现至少1例阳性斑贴试验(PPT)反应，1087例(75.6%)患者出现至少1例相关PPT反应。最常见的PPT过敏原是镍(21.5%)，其次是芳樟醇氢过氧化物(20.4%)和秘鲁香脂(11.5%)。统计上，丙二醇的致敏率随时间增加，而其他12种过敏原的致敏率下降(所有P值限制:回顾性设计，单一机构三级转诊人群，以及整个研究期间过敏原和供应商的变化。)结论:ACD领域在不断发展。定期分析斑贴试验数据对于确定新出现和减少的接触性过敏原趋势至关重要。

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Patch Testing Results From the Massachusetts General Hospital Occupational and Contact Dermatitis Clinic, 2017-2022.

Background: Patch testing is gold standard for identifying the source of allergic contact dermatitis (ACD). Objective: To report patch testing results from the Massachusetts General Hospital (MGH) Occupational and Contact Dermatitis Clinic from 2017 to 2022. Methods: Retrospective analysis of patients referred to MGH for patch testing, 2017-2022. Results: In total, 1438 patients were included. At least 1 positive patch test (PPT) reaction was observed in 1168 (81.2%) patients and at least 1 relevant PPT reaction was observed in 1087 (75.6%) patients. The most common allergen with a PPT was nickel (21.5%), followed by hydroperoxides of linalool (20.4%) and balsam of Peru (11.5%). Sensitization rates statistically increased over time for propylene glycol and decreased for 12 other allergens (all P values <0.0004). Limitations: Retrospective design, single institution tertiary referral population, and variations in allergens and suppliers across the study period. Conclusion: The field of ACD is constantly evolving. Regular analysis of patch test data is crucial to identify emerging and diminishing contact allergen trends.

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来源期刊

Dermatitis 医学-皮肤病学

CiteScore

5.30

自引率

11.50%

发文量

251

审稿时长

>12 weeks

期刊介绍： Dermatitis is owned by the American Contact Dermatitis Society and is the home journal of 4 other organizations, namely Societa Italiana di Dermatologica Allergologica Professionale e Ambientale, Experimental Contact Dermatitis Research Group, International Contact Dermatitis Research Group, and North American Contact Dermatitis Group. Dermatitis focuses on contact, atopic, occupational, and drug dermatitis, and welcomes manuscript submissions in these fields, with emphasis on reviews, studies, reports, and letters. Annual sections include Contact Allergen of the Year and Contact Allergen Alternatives, for which papers are chosen or invited by the respective section editor. Other sections unique to the journal are Pearls & Zebras, Product Allergen Watch, and news, features, or meeting abstracts from participating organizations.