膳食微量营养素与子宫内膜异位症的关系:一项病例对照研究。

IF 1.6 Q3 OBSTETRICS & GYNECOLOGY
Ghazal Roshanzadeh, Shahideh Jahanian Sadatmahalleh, Ashraf Moini, Azadeh Mottaghi, Farahnaz Rostami
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引用次数: 1

摘要

背景:关于子宫内膜异位症女性微量营养素摄入的研究较少,子宫内膜异位症的病因尚不清楚膳食微量营养素与子宫内膜异位症风险之间的关系。目的:探讨膳食微量营养素与子宫内膜异位症发病的关系。材料和方法:本病例对照研究于2017年5月至2018年5月在伊朗德黑兰Arash医院妇科诊所进行的156名患有或未患有子宫内膜异位症的女性(18-45岁)进行。根据腹腔镜检查结果,将参与者分为2组(每组78人),有盆腔子宫内膜异位症的女性为病例组,无盆腔子宫内膜异位症的女性为对照组。膳食数据的收集采用了一份经过验证的168项半定量食物频率问卷和标准服务。逻辑回归模型用于确定微量营养素与子宫内膜异位症风险之间的关系。结果:数据分析显示,微量营养素如钾(OR: 0.74;置信区间:0.56—-0.99;p = 0.01)、钙(OR: 0.70;置信区间:0.52—-0.94;p = 0.003),维生素C也是如此(OR: 0.70;置信区间:0.52—-0.94;p = 0.02), B2 (OR: 0.73;置信区间:0.55—-0.98;p = 0.01), B12 (OR: 0.71;置信区间:0.53—-0.95;P = 0.02)与子宫内膜异位症有关,所以那些摄入微量营养素较少的人患子宫内膜异位症的风险更高。结论:膳食中钙、钾、维生素B12、B2、B6、C的摄入量与子宫内膜异位症的发生风险呈负相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The relationship between dietary micronutrients and endometriosis: A case-control study.

Background: Fewer studies were on micronutrient intake in women with endometriosis, and the etiology of endometriosis remains unclear between dietary micronutrients and the risk of endometriosis.

Objective: This study aimed to investigate the relationship between dietary micronutrients and the risk of endometriosis.

Materials and methods: This case-control study was conducted on 156 women (18-45 yr) with and without endometriosis in the gynecology clinic of Arash hospital between May 2017 and May 2018 in Tehran, Iran. According to the laparoscopic findings, the participants were divided into 2 groups (n = 78/each), women with pelvic endometriosis as the case group and women without endometriosis pelvic as the control group. Dietary data were collected using a validated 168-item semiquantitative food frequency questionnaire with the standard serving. A logistic regression model was used to determine the association between micronutrients and the risk of endometriosis.

Results: Data analysis showed a significant relationship between micronutrients such as: potassium (OR: 0.74; CI: 0.56-0.99; p = 0.01), calcium (OR: 0.70; CI: 0.52-0.94; p = 0.003), and also among the vitamin C (OR: 0.70; CI: 0.52-0.94; p = 0.02), B2 (OR: 0.73; CI: 0.55-0.98; p = 0.01), and B12 (OR: 0.71; CI: 0.53-0.95; p = 0.02) with endometriosis, so those who used fewer micronutrients were at higher risk of endometriosis.

Conclusion: The findings showed that the dietary intakes of calcium, potassium, vitamins B12, B2, B6, and C are inversely related to the risk of endometriosis.

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来源期刊
CiteScore
2.40
自引率
7.70%
发文量
93
审稿时长
16 weeks
期刊介绍: The International Journal of Reproductive BioMedicine (IJRM), formerly published as "Iranian Journal of Reproductive Medicine (ISSN: 1680-6433)", is an international monthly scientific journal for who treat and investigate problems of infertility and human reproductive disorders. This journal accepts Original Papers, Review Articles, Short Communications, Case Reports, Photo Clinics, and Letters to the Editor in the fields of fertility and infertility, ethical and social issues of assisted reproductive technologies, cellular and molecular biology of reproduction including the development of gametes and early embryos, assisted reproductive technologies in model system and in a clinical environment, reproductive endocrinology, andrology, epidemiology, pathology, genetics, oncology, surgery, psychology, and physiology. Emerging topics including cloning and stem cells are encouraged.
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