{"title":"用表面活性剂混合物提高香胶提取物(安息香)的稳定性。","authors":"Nora Susanti, Jamalum Purba, M Yosia Gopas Oetama","doi":"10.4103/japtr.japtr_539_22","DOIUrl":null,"url":null,"abstract":"Styrax benzoin is a type of incense produced in North Tapanuli, Indonesia. The content of metabolite compounds provides wide use in pharmaceuticals. The occurrence of deposits in the extract makes this preparation unstable; this instability creates problems, especially in the concentration of the extract and is impractical so it needs to be redissolved. The method of using surfactants can be used as a suspending agent, a mixture of two types of surfactants gives variations in hydrophilic and lipophilic balance (HLB), by finding the optimum HLB value to create optimum solution stability and organoleptic, various mixture ratios were carried out with test parameters such as organoleptic, pH, viscosity, particle size, and components of chemical compounds. The results show that the optimum HLB of S. benzoin is 12.7 in surfactants Tween 80 and Span 80.","PeriodicalId":14877,"journal":{"name":"Journal of Advanced Pharmaceutical Technology & Research","volume":null,"pages":null},"PeriodicalIF":1.4000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/bd/48/JAPTR-14-24.PMC10026331.pdf","citationCount":"0","resultStr":"{\"title\":\"Increasing the stability of incense gum extract (<i>Styrax benzoin</i>) with a mixture of surfactants.\",\"authors\":\"Nora Susanti, Jamalum Purba, M Yosia Gopas Oetama\",\"doi\":\"10.4103/japtr.japtr_539_22\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Styrax benzoin is a type of incense produced in North Tapanuli, Indonesia. The content of metabolite compounds provides wide use in pharmaceuticals. The occurrence of deposits in the extract makes this preparation unstable; this instability creates problems, especially in the concentration of the extract and is impractical so it needs to be redissolved. The method of using surfactants can be used as a suspending agent, a mixture of two types of surfactants gives variations in hydrophilic and lipophilic balance (HLB), by finding the optimum HLB value to create optimum solution stability and organoleptic, various mixture ratios were carried out with test parameters such as organoleptic, pH, viscosity, particle size, and components of chemical compounds. The results show that the optimum HLB of S. benzoin is 12.7 in surfactants Tween 80 and Span 80.\",\"PeriodicalId\":14877,\"journal\":{\"name\":\"Journal of Advanced Pharmaceutical Technology & Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/bd/48/JAPTR-14-24.PMC10026331.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Advanced Pharmaceutical Technology & Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/japtr.japtr_539_22\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2023/1/20 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"Pharmacology, Toxicology and Pharmaceutics\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Advanced Pharmaceutical Technology & Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/japtr.japtr_539_22","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/1/20 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"Pharmacology, Toxicology and Pharmaceutics","Score":null,"Total":0}
Increasing the stability of incense gum extract (Styrax benzoin) with a mixture of surfactants.
Styrax benzoin is a type of incense produced in North Tapanuli, Indonesia. The content of metabolite compounds provides wide use in pharmaceuticals. The occurrence of deposits in the extract makes this preparation unstable; this instability creates problems, especially in the concentration of the extract and is impractical so it needs to be redissolved. The method of using surfactants can be used as a suspending agent, a mixture of two types of surfactants gives variations in hydrophilic and lipophilic balance (HLB), by finding the optimum HLB value to create optimum solution stability and organoleptic, various mixture ratios were carried out with test parameters such as organoleptic, pH, viscosity, particle size, and components of chemical compounds. The results show that the optimum HLB of S. benzoin is 12.7 in surfactants Tween 80 and Span 80.
期刊介绍:
Journal of Advanced Pharmaceutical Technology & Research (JAPTR) is an Official Publication of Society of Pharmaceutical Education & Research™. It is an international journal published Quarterly. Journal of Advanced Pharmaceutical Technology & Research (JAPTR) is available in online and print version. It is a peer reviewed journal aiming to communicate high quality original research work, reviews, short communications, case report, Ethics Forum, Education Forum and Letter to editor that contribute significantly to further the scientific knowledge related to the field of Pharmacy i.e. Pharmaceutics, Pharmacology, Pharmacognosy, Pharmaceutical Chemistry. Articles with timely interest and newer research concepts will be given more preference.