80 岁及以上患者的鸟样脉络膜视网膜炎

IF 2.6 4区 医学 Q2 OPHTHALMOLOGY
Ocular Immunology and Inflammation Pub Date : 2024-09-01 Epub Date: 2023-05-19 DOI:10.1080/09273948.2023.2215322
Louis Debillon, Jennifer E Thorne, Elodie Bousquet, Pierre Duraffour, Souhila Kecili, Dominique Monnet, Antoine P Brézin
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引用次数: 0

摘要

目的:评估鸟枪状脉络膜视网膜炎(BSCR)在 80 岁及以上患者中的表现:在 CO-BIRD 前瞻性队列(ClinicalTrials.gov Identifier:NCT05153057)随访的 BSCR 患者中,我们分析了 80 岁及以上的亚组患者:以标准化方式对患者进行评估。眼底自发荧光(FAF)上的低自发荧光点定义为汇合性萎缩:我们纳入了 442 例 CO-BIRD 患者中的 39 例(8.8%)。平均年龄为 83.8 ± 3.7 岁。BCVA 对数平均值为 0.52 ± 0.76,其中 30 名患者(76.9%)至少有一只眼的视力达到或优于 20/40。35名患者(89.7%)未接受任何治疗。后极部汇合性萎缩、视网膜后椭圆体区破坏和脉络膜新生血管与 BCVA 对数大于 0.3 有关(p 结论:在 80 岁以上的患者中,我们观察到视网膜后椭圆体区破坏和脉络膜新生血管与 BCVA 对数大于 0.3 有关:在 80 岁及以上的患者中,我们观察到了惊人的异质性结果,但大多数患者的 BCVA 仍能让他们开车。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Birdshot Chorioretinitis in Patients Aged 80 and Older.

Purpose: To assess the manifestations of birdshot chorioretinitis (BSCR) in patients aged 80 and over.

Design: Among patients with BSCR followed in the CO-BIRD prospective cohort (ClinicalTrials.gov Identifier: NCT05153057), we analyzed the subgroup of patients aged 80 and over.

Methods: Patients were assessed in a standardized manner. Confluent atrophy was defined as hypoautofluorescent spots on fundus autofluorescence (FAF).

Results: We included 39 (8.8%) of the 442 enrolled CO-BIRD patients. The mean age was 83.8 ± 3.7 years. The mean logMAR BCVA was 0.52 ± 0.76, with 30 patients (76.9%) having 20/40 or better in at least one eye. Thirty-five (89.7%) patients were receiving no treatment. Confluent atrophy in the posterior pole, disrupted retrofoveal ellipsoid zone and choroidal neovascularization were associated with logMAR BCVA >0.3 (p < .0001).

Conclusion: In patients aged 80 and over we observed a striking heterogeneity of outcomes, but most retained a BCVA that allowed them to drive.

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来源期刊
CiteScore
6.20
自引率
15.20%
发文量
285
审稿时长
6-12 weeks
期刊介绍: Ocular Immunology & Inflammation ranks 18 out of 59 in the Ophthalmology Category.Ocular Immunology and Inflammation is a peer-reviewed, scientific publication that welcomes the submission of original, previously unpublished manuscripts directed to ophthalmologists and vision scientists. Published bimonthly, the journal provides an international medium for basic and clinical research reports on the ocular inflammatory response and its control by the immune system. The journal publishes original research papers, case reports, reviews, letters to the editor, meeting abstracts, and invited editorials.
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