基于深度学习的超声心动图数据测量及其在诊断心脏性猝死中的应用。

IF 6.5 3区 工程技术 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Lu Zhang, Bohan Liu, Sulei Li, Jing Wang, Yang Mu, Xuan Zhou, Li Sheng
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引用次数: 0

摘要

本研究旨在评估深度学习应用于心脏性猝死(SCD)患者超声心动图数据测量的潜力。320 名符合纳入和排除标准的 SCD 患者接受了临床评估,包括年龄、性别、体重指数、高血压、糖尿病、心脏功能分类和超声心动图检查。通过将患者分为两组:训练组(n=160)和验证组(n=160),以及同期的两组健康志愿者(每组 n=200),观察了深度学习模型的诊断价值。逻辑回归分析表明,MLVWT、LVEDD、LVEF、LVOT-PG、LAD、E/e'都是SCD的危险因素。随后,利用收集到的训练组图像对基于深度学习的模型进行了训练。根据验证组的识别准确率选出了最佳模型,结果显示训练组的准确率为 91.8%,灵敏度为 80.00%,特异性为 91.90%。模型 ROC 曲线的 AUC 值在训练组为 0.877,在验证组为 0.995。该方法在预测 SCD 方面具有很高的诊断价值和准确性,对早期发现和诊断 SCD 具有重要的临床意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Deep learning-based measurement of echocardiographic data and its application in the diagnosis of sudden cardiac death.

This study aimed to evaluate the potential of deep learning applied to the measurement of echocardiographic data in patients with sudden cardiac death (SCD). 320 SCD patients who met the inclusion and exclusion criteria underwent clinical evaluation, including age, sex, BMI, hypertension, diabetes, cardiac function classification, and echocardiography. The diagnostic value of deep learning model was observed by dividing the patients into two groups: training group (n=160) and verification group (n=160), as well as two groups of healthy volunteers (n=200 for each group) during the same period. Logistic regression analysis showed that MLVWT, LVEDD, LVEF, LVOT-PG, LAD, E/e' were all risk factors for SCD. Subsequently, a deep learning-based model was trained using the collected images of the training group. The optimal model was selected based on the identification accuracy of the validation group and showed an accuracy of 91.8%, sensitivity of 80.00%, and specificity of 91.90% in the training group. The AUC value of the ROC curve of the model was 0.877 for the training group and 0.995 for the validation groups. This approach demonstrates high diagnostic value and accuracy in predicting SCD, which is clinically important for the early detection and diagnosis of SCD.

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来源期刊
Biotechnology & Genetic Engineering Reviews
Biotechnology & Genetic Engineering Reviews BIOTECHNOLOGY & APPLIED MICROBIOLOGY-GENETICS & HEREDITY
CiteScore
6.50
自引率
3.10%
发文量
33
期刊介绍: Biotechnology & Genetic Engineering Reviews publishes major invited review articles covering important developments in industrial, agricultural and medical applications of biotechnology.
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