公共资助的药物护理计划对儿童和青少年处方兴奋剂使用的影响:一项基于人群的观察自然实验。

IF 3.3 3区 医学 Q2 PSYCHIATRY
Tony Antoniou, Daniel McCormack, Sophie Kitchen, Kathleen Pajer, William Gardner, Yona Lunsky, Melanie Penner, Mina Tadrous, Muhammad Mamdani, David N Juurlink, Tara Gomes
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引用次数: 0

摘要

目的:兴奋剂是治疗注意力缺陷多动障碍的一线药物。然而,药物覆盖率的差异可能导致不公平的治疗机会。2018年1月,加拿大安大略省政府实施了一项公共资助计划(OHIP+),为0岁至24岁的儿童和青年免费普及药物。2019年4月,该计划进行了修订,只涵盖没有私人保险的儿童和青年。我们研究了这些政策变化是否与安大略省儿童和青少年处方兴奋剂分配的变化有关。方法:我们在2013年1月至2020年3月期间对安大略省的儿童和青少年进行了一项基于人群的观察性自然实验研究。我们使用介入自回归综合移动平均模型来估计OHIP+及其后续修改与兴奋剂分配趋势之间的关联。结果:在2017年12月至2019年3月期间,OHIP+的实施与每月每100000人中53.6人的兴奋剂分配率立即显著增加(95%置信区间[CI],每100000人36.8至70.5)和14.2%(95%可信区间,12.8%至15.6%)的相对兴奋剂分配率增加有关(每100000人中有1198.6人,1368.7人)。2019年4月OHIP+计划修正案与每月兴奋剂分配趋势的增加有关,即每100000人中有10.2人(95%置信区间,5.0至15.5),2019年3月至2020年3月期间,兴奋剂分配率增加了7.5%(95%可信区间,6.2%至8.7%)(每100000人1368.7人对1470.8人)。这些关联在生活在收入最高社区的男性、儿童和青年以及20至24岁的个人中最为明显。结论:公共资助的制药计划与更多的儿童和青年被分配兴奋剂有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Impact of a Publicly-Funded Pharmacare Program on Prescription Stimulant use Among Children and Youth: A Population-Based Observational Natural Experiment.

Impact of a Publicly-Funded Pharmacare Program on Prescription Stimulant use Among Children and Youth: A Population-Based Observational Natural Experiment.

Impact of a Publicly-Funded Pharmacare Program on Prescription Stimulant use Among Children and Youth: A Population-Based Observational Natural Experiment.

Impact of a Publicly-Funded Pharmacare Program on Prescription Stimulant use Among Children and Youth: A Population-Based Observational Natural Experiment.

Objective: Stimulants are first-line pharmacotherapy for individuals with attention-deficit hyperactivity disorder. However, disparities in drug coverage may contribute to inequitable treatment access. In January 2018, the government of Ontario, Canada, implemented a publicly-funded program (OHIP+) providing universal access to medications at no cost to children and youth between the ages of 0 and 24. In April 2019, the program was amended to cover only children and youth without private insurance. We studied whether these policy changes were associated with changes in prescription stimulant dispensing to Ontario children and youth.

Methods: We conducted a population-based observational natural experiment study of stimulant dispensing to children and youth in Ontario between January 2013 and March 2020. We used interventional autoregressive integrated moving average models to estimate the association between OHIP+ and its subsequent modification with stimulant dispensing trends.

Results: The implementation of OHIP+ was associated with a significant immediate increase in the monthly rate of stimulant dispensing of 53.6 individuals per 100,000 population (95% confidence interval [CI], 36.8 to 70.5 per 100,000) and a 14.2% (95% CI, 12.8% to 15.6%) relative percent increase in stimulant dispensing rates between December 2017 and March 2019 (1198.6 vs. 1368.7 per 100,000 population). The April 2019 OHIP+ program amendment was associated with an increase in monthly stimulant dispensing trends of 10.2 individuals per 100,000 population (95% CI, 5.0 to 15.5), with rates increasing 7.5% (95% CI, 6.2% to 8.7%) between March 2019 and March 2020 (1368.7 vs. 1470.8 per 100,000 population). These associations were most pronounced among males, children and youth living in the highest income neighbourhoods and individuals aged 20 to 24.

Conclusion: A publicly-funded pharmacare program was associated with more children and youth being dispensed stimulants.

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来源期刊
CiteScore
7.00
自引率
2.50%
发文量
69
审稿时长
6-12 weeks
期刊介绍: Established in 1956, The Canadian Journal of Psychiatry (The CJP) has been keeping psychiatrists up-to-date on the latest research for nearly 60 years. The CJP provides a forum for psychiatry and mental health professionals to share their findings with researchers and clinicians. The CJP includes peer-reviewed scientific articles analyzing ongoing developments in Canadian and international psychiatry.
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