Kareem El Naamani, Panagiotis Mastorakos, Nimer Adeeb, Mathews Lan, James Castiglione, Omaditya Khanna, Jose Danilo Bengzon Diestro, Rachel M McLellan, Mahmoud Dibas, Justin E Vranic, Assala Aslan, Hugo H Cuellar-Saenz, Adrien Guenego, Joseph Carnevale, Guillaume Saliou, Christian Ulfert, Markus Möhlenbruch, Paul M Foreman, Jay A Vachhani, Muhammad U Hafeez, Muhammad Waqas, Vincent M Tutino, James D Rabinov, Yifan Ren, Caterina Michelozzi, Julian Spears, Pietro Panni, Christoph J Griessenauer, Hamed Asadi, Robert W Regenhardt, Christopher J Stapleton, Sherief Ghozy, Adnan Siddiqui, Nirav J Patel, Peter Kan, Srikanth Boddu, Jared Knopman, Mohammad A Aziz-Sultan, Mario Zanaty, Ritam Ghosh, Rawad Abbas, Abdelaziz Amllay, Stavropoula I Tjoumakaris, Michael R Gooch, Nicole M Cancelliere, Nabeel A Herial, Robert H Rosenwasser, Hekmat Zarzour, Richard F Schmidt, Vitor Mendes Pereira, Aman B Patel, Pascal Jabbour, Adam A Dmytriw
{"title":"使用 Woven EndoBridge (WEB) 装置干预后 6 个月完全闭塞的脑动脉瘤的长期随访:一项回顾性多中心观察研究。","authors":"Kareem El Naamani, Panagiotis Mastorakos, Nimer Adeeb, Mathews Lan, James Castiglione, Omaditya Khanna, Jose Danilo Bengzon Diestro, Rachel M McLellan, Mahmoud Dibas, Justin E Vranic, Assala Aslan, Hugo H Cuellar-Saenz, Adrien Guenego, Joseph Carnevale, Guillaume Saliou, Christian Ulfert, Markus Möhlenbruch, Paul M Foreman, Jay A Vachhani, Muhammad U Hafeez, Muhammad Waqas, Vincent M Tutino, James D Rabinov, Yifan Ren, Caterina Michelozzi, Julian Spears, Pietro Panni, Christoph J Griessenauer, Hamed Asadi, Robert W Regenhardt, Christopher J Stapleton, Sherief Ghozy, Adnan Siddiqui, Nirav J Patel, Peter Kan, Srikanth Boddu, Jared Knopman, Mohammad A Aziz-Sultan, Mario Zanaty, Ritam Ghosh, Rawad Abbas, Abdelaziz Amllay, Stavropoula I Tjoumakaris, Michael R Gooch, Nicole M Cancelliere, Nabeel A Herial, Robert H Rosenwasser, Hekmat Zarzour, Richard F Schmidt, Vitor Mendes Pereira, Aman B Patel, Pascal Jabbour, Adam A Dmytriw","doi":"10.1007/s12975-023-01153-5","DOIUrl":null,"url":null,"abstract":"<p><p>The Woven EndoBridge (WEB) device has been widely used to treat intracranial wide neck bifurcation aneurysms. Initial studies have demonstrated that approximately 90% of patients have same or improved long-term aneurysm occlusion after the initial 6-month follow up. The aim of this study is to assess the long-term follow-up in aneurysms that have achieved complete occlusion at 6 months. We also compared the predictive value of different imaging modalities used. This is an analysis of a prospectively maintained database across 13 academic institutions. We included patients with previously untreated cerebral aneurysms embolized using the WEB device who achieved complete occlusion at first follow-up and had available long-term follow-up. A total of 95 patients with a mean age of 61.6 ± 11.9 years were studied. The mean neck diameter and height were 3.9 ± 1.3 mm and 6.0 ± 1.8 mm, respectively. The mean time to first and last follow-up was 5.4 ± 1.8 and 14.1 ± 12.9 months, respectively. Out of all the aneurysms that were completely occluded at 6 months, 84 (90.3%) showed complete occlusion at the final follow-up, and 11(11.5%) patients did not achieve complete occlusion. The positive predictive value (PPV) of complete occlusion at first follow was 88.4%. Importantly, this did not differ between digital subtraction angiography (DSA), magnetic resonance angiography (MRA), or computed tomography angiography (CTA). This study underlines the importance of repeat imaging in patients treated with the WEB device even if complete occlusion is achieved short term. Follow-up can be performed using DSA, MRA or CTA with no difference in positive predictive value.</p>","PeriodicalId":23237,"journal":{"name":"Translational Stroke Research","volume":null,"pages":null},"PeriodicalIF":3.8000,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Long-Term Follow-Up of Cerebral Aneurysms Completely Occluded at 6 Months After Intervention with the Woven EndoBridge (WEB) Device: a Retrospective Multicenter Observational Study.\",\"authors\":\"Kareem El Naamani, Panagiotis Mastorakos, Nimer Adeeb, Mathews Lan, James Castiglione, Omaditya Khanna, Jose Danilo Bengzon Diestro, Rachel M McLellan, Mahmoud Dibas, Justin E Vranic, Assala Aslan, Hugo H Cuellar-Saenz, Adrien Guenego, Joseph Carnevale, Guillaume Saliou, Christian Ulfert, Markus Möhlenbruch, Paul M Foreman, Jay A Vachhani, Muhammad U Hafeez, Muhammad Waqas, Vincent M Tutino, James D Rabinov, Yifan Ren, Caterina Michelozzi, Julian Spears, Pietro Panni, Christoph J Griessenauer, Hamed Asadi, Robert W Regenhardt, Christopher J Stapleton, Sherief Ghozy, Adnan Siddiqui, Nirav J Patel, Peter Kan, Srikanth Boddu, Jared Knopman, Mohammad A Aziz-Sultan, Mario Zanaty, Ritam Ghosh, Rawad Abbas, Abdelaziz Amllay, Stavropoula I Tjoumakaris, Michael R Gooch, Nicole M Cancelliere, Nabeel A Herial, Robert H Rosenwasser, Hekmat Zarzour, Richard F Schmidt, Vitor Mendes Pereira, Aman B Patel, Pascal Jabbour, Adam A Dmytriw\",\"doi\":\"10.1007/s12975-023-01153-5\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The Woven EndoBridge (WEB) device has been widely used to treat intracranial wide neck bifurcation aneurysms. Initial studies have demonstrated that approximately 90% of patients have same or improved long-term aneurysm occlusion after the initial 6-month follow up. The aim of this study is to assess the long-term follow-up in aneurysms that have achieved complete occlusion at 6 months. We also compared the predictive value of different imaging modalities used. This is an analysis of a prospectively maintained database across 13 academic institutions. We included patients with previously untreated cerebral aneurysms embolized using the WEB device who achieved complete occlusion at first follow-up and had available long-term follow-up. A total of 95 patients with a mean age of 61.6 ± 11.9 years were studied. The mean neck diameter and height were 3.9 ± 1.3 mm and 6.0 ± 1.8 mm, respectively. The mean time to first and last follow-up was 5.4 ± 1.8 and 14.1 ± 12.9 months, respectively. Out of all the aneurysms that were completely occluded at 6 months, 84 (90.3%) showed complete occlusion at the final follow-up, and 11(11.5%) patients did not achieve complete occlusion. The positive predictive value (PPV) of complete occlusion at first follow was 88.4%. Importantly, this did not differ between digital subtraction angiography (DSA), magnetic resonance angiography (MRA), or computed tomography angiography (CTA). This study underlines the importance of repeat imaging in patients treated with the WEB device even if complete occlusion is achieved short term. Follow-up can be performed using DSA, MRA or CTA with no difference in positive predictive value.</p>\",\"PeriodicalId\":23237,\"journal\":{\"name\":\"Translational Stroke Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":3.8000,\"publicationDate\":\"2024-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Translational Stroke Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s12975-023-01153-5\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2023/5/11 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q1\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Translational Stroke Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s12975-023-01153-5","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/5/11 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
Long-Term Follow-Up of Cerebral Aneurysms Completely Occluded at 6 Months After Intervention with the Woven EndoBridge (WEB) Device: a Retrospective Multicenter Observational Study.
The Woven EndoBridge (WEB) device has been widely used to treat intracranial wide neck bifurcation aneurysms. Initial studies have demonstrated that approximately 90% of patients have same or improved long-term aneurysm occlusion after the initial 6-month follow up. The aim of this study is to assess the long-term follow-up in aneurysms that have achieved complete occlusion at 6 months. We also compared the predictive value of different imaging modalities used. This is an analysis of a prospectively maintained database across 13 academic institutions. We included patients with previously untreated cerebral aneurysms embolized using the WEB device who achieved complete occlusion at first follow-up and had available long-term follow-up. A total of 95 patients with a mean age of 61.6 ± 11.9 years were studied. The mean neck diameter and height were 3.9 ± 1.3 mm and 6.0 ± 1.8 mm, respectively. The mean time to first and last follow-up was 5.4 ± 1.8 and 14.1 ± 12.9 months, respectively. Out of all the aneurysms that were completely occluded at 6 months, 84 (90.3%) showed complete occlusion at the final follow-up, and 11(11.5%) patients did not achieve complete occlusion. The positive predictive value (PPV) of complete occlusion at first follow was 88.4%. Importantly, this did not differ between digital subtraction angiography (DSA), magnetic resonance angiography (MRA), or computed tomography angiography (CTA). This study underlines the importance of repeat imaging in patients treated with the WEB device even if complete occlusion is achieved short term. Follow-up can be performed using DSA, MRA or CTA with no difference in positive predictive value.
期刊介绍:
Translational Stroke Research covers basic, translational, and clinical studies. The Journal emphasizes novel approaches to help both to understand clinical phenomenon through basic science tools, and to translate basic science discoveries into the development of new strategies for the prevention, assessment, treatment, and enhancement of central nervous system repair after stroke and other forms of neurotrauma.
Translational Stroke Research focuses on translational research and is relevant to both basic scientists and physicians, including but not restricted to neuroscientists, vascular biologists, neurologists, neuroimagers, and neurosurgeons.