肠扩张对电影mri测量小肠运动的影响:两种量化技术的评估。

BJR open Pub Date : 2022-01-01 DOI:10.1259/bjro.20210049
Kyra L van Rijn, Jaap Stoker, Alex Menys, Catharina S de Jonge
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引用次数: 0

摘要

目的:通过比较健康和患病人群的常规肠蠕动评分(包括肠壁和肠腔)和肠壁特异性肠蠕动评分,评估肠扩张对cine-MRI小肠蠕动测量的影响。方法:纳入4个人群:10例狭窄和狭窄前扩张的克罗恩病患者进行节段性肠蠕动分析,14例甘露醇制备的健康受试者、15例禁食的健康受试者和8例以肠袢扩张为特征的慢性假性肠梗阻(CIPO)患者进行整体小肠蠕动分析。所有受试者都进行了电影核磁共振扫描,计算出两种运动评分:常规评分(包括肠壁和肠腔)和肠壁特异性评分。两个分数之间的差异是按人口计算的,并通过单向方差分析和Tukey-Kramer分析在组间进行比较。结果:在克罗恩病患者中,常规和壁特异性运动评分之间的中位(IQR)变化在狭窄内为0%(-2至+4%),在狭窄扩张处为0%(-1至+7%)。对于全球小肠,在甘露醇制备的健康受试者中为-1%(- 5%至0%),在禁食的健康受试者中为-2%(-6至+2%),在CIPO患者中为+14%(+6至+20%)。CIPO患者的两种运动评分差异与其他四组有显著差异(p = 0.002至p < 0.001)。结论:在克罗恩病患者和健康受试者中,传统的小肠运动评分似乎是可靠的。在肠环整体和严重扩张的患者中,肠壁特异性运动性评分可以更好地代表小肠运动性。知识的进步:这些发现支持研究人员和临床医生在不同人群中使用电影mri运动分析做出明智的选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Impact of bowel dilation on small bowel motility measurements with cine-MRI: assessment of two quantification techniques.

Impact of bowel dilation on small bowel motility measurements with cine-MRI: assessment of two quantification techniques.

Impact of bowel dilation on small bowel motility measurements with cine-MRI: assessment of two quantification techniques.

Impact of bowel dilation on small bowel motility measurements with cine-MRI: assessment of two quantification techniques.

Objectives: To evaluate the effect of bowel dilation on cine-MRI small bowel motility measurements, by comparing a conventional motility score (including bowel wall and lumen) with a bowel wall-specific motility score in healthy and diseased populations.

Methods: Four populations were included: 10 Crohn's patients with a stricture and prestricture dilation for segmental motility analysis, and 14 mannitol-prepared healthy subjects, 15 fasted healthy subjects and eight chronic intestinal pseudo-obstruction (CIPO) patients (characterized by dilated bowel loops) for global small bowel motility analysis. All subjects underwent a cine-MRI scan from which two motility scores were calculated: a conventional score (including bowel wall and lumen) and a bowel wall-specific score. The difference between the two scores was calculated per population and compared between groups with a one-way ANOVA and Tukey-Kramer analysis.

Results: In Crohn's patients, the median (IQR) change between the conventional and wall-specific motility score was 0% (-2 to +4%) within the stricture and 0% (-1 to +7%) in the prestricture dilation. For the global small bowel, this was -1% (-5 to 0%) in mannitol-prepared healthy subjects, -2% (-6 to +2%) in fasted healthy subjects and +14% (+6 to+20%) in CIPO patients. The difference between the two motility scores in CIPO patients differed significantly from the four other groups (p = 0.002 to p < 0.001).

Conclusions: The conventional small bowel motility score seems robust in Crohn's disease patients and healthy subjects. In patients with globally and grossly dilated bowel loops, a bowel-wall specific motility score may give a better representation of small bowel motility.

Advances in knowledge: These findings support researchers and clinicians with making informed choices for using cine-MRI motility analysis in different populations.

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