甲状腺金刚素瘤样尤文氏肉瘤-一种不熟悉的头颈部上皮和间质肿瘤的模拟物。

IF 0.6 4区医学 Q4 PATHOLOGY

Malaysian Journal of Pathology Pub Date : 2023-04-01

I Mohammed, B Baskovich, A Alkhasawneh, A Gopinath

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引用次数: 0

摘要

简介:Adamantinoma-like Ewing Sarcoma (ALES)是Ewing家族肿瘤(EFT)的一种罕见变体，具有EWSR1-FLI1易位和复杂的上皮分化。文献中很少报道累及甲状腺的ALES病例。病例报告:我们报告一例累及甲状腺的ALES，患者为61岁男性，其表现为甲状腺左叶肿大结节，并行半甲状腺切除术。讨论:ALES表现出与许多上皮和间充质肿瘤的形态学相似性，这在甲状腺和头颈部病理中产生了潜在的诊断缺陷。鉴于这种肿瘤的罕见性，对于这些病例在甲状腺切除术后的进一步手术治疗，也缺乏公认的指导方针。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

本刊更多论文

Adamantinoma-like Ewing sarcoma of thyroid gland-An unfamiliar mimicker of epithelial and mesenchymal neoplasms of the head and neck.

Introduction: Adamantinoma-like Ewing Sarcoma (ALES) is a rare variant of the Ewing family of tumours (EFT) harbouring the EWSR1-FLI1 translocation and with complex epithelial differentiation. Very few cases of ALES involving thyroid have been reported in literature.

Case report: We report a case of ALES involving the thyroid in a 61-year-old male who presented with an enlarging nodule in the left lobe of the thyroid and underwent hemithyroidectomy.

Discussion: ALES demonstrates morphologic similarity to a multitude of epithelial and mesenchymal tumours, creating a potential diagnostic pitfall in thyroid and head and neck pathology. Given the rarity of this tumour, there is also a lack of accepted guidelines regarding further surgical management of these cases following hemithyroidectomy.

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来源期刊

Malaysian Journal of Pathology PATHOLOGY-

CiteScore

3.60

自引率

5.60%

发文量

期刊介绍： The Malaysian Journal of Pathology is the official journal of the College of Pathologists, Academy of Medicine Malaysia. The primary purpose of The Journal is to publish the results of study and research in Pathology, especially those that have particular relevance to human disease occurring in Malaysia and other countries in this region. The term PATHOLOGY will be interpreted in its broadest sense to include Chemical Pathology, Cytology, Experimental Pathology, Forensic Pathology, Haematology, Histopathology, Immunology, Medical Microbiology and Parasitology. The Journal aims to bring under one cover publications of regional interest embracing the various sub-specialities of Pathology. It is expected that the articles published would be of value not only to pathologists, but also to medical practitioners in search of a scientific basis for the problems encountered in their practice, and to those with an interest in diseases which occur in the tropics.