异种移植和外移植:扩大供体器官数量的策略。

IF 3.3 4区医学 Q2 MEDICINE, RESEARCH & EXPERIMENTAL

Xenotransplantation Pub Date : 2023-01-01 DOI:10.1111/xen.12786

Daniel J Garry, Joshua I Weiner, Sarah M Greising, David H Sachs, Mary G Garry

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引用次数: 1

摘要

心血管疾病很常见，死亡率很高。由于可用于原位心脏移植的器官数量有限，替代疗法引起了人们的强烈兴趣。在这篇评论中，我们对比了异种移植和囊胚互补，以产生将作为器官移植供体的猪。这些策略具有巨大的前景，有可能为慢性终末期疾病提供无限数量的器官。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Xenotransplantation and exotransplantation: Strategies to expand the number of donor organs.

Cardiovascular disease is common and has a high mortality. Due to the limited number of organs available for orthotopic heart transplantation, alternative therapies have received intense interest. In this commentary we contrast xenotransplantation and blastocyst complementation to produce pigs that will serve as donors for organ transplantation. These strategies hold tremendous promise and have the potential to provide an unlimited number of organs for chronic, terminal diseases.

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来源期刊

Xenotransplantation 医学-医学：研究与实验

CiteScore

6.80

自引率

15.40%

发文量

审稿时长

>12 weeks

期刊介绍： Xenotransplantation provides its readership with rapid communication of new findings in the field of organ and tissue transplantation across species barriers.The journal is not only of interest to those whose primary area is xenotransplantation, but also to veterinarians, microbiologists and geneticists. It also investigates and reports on the controversial theological, ethical, legal and psychological implications of xenotransplantation.