食管癌术后复发时al18f - nota - fapi -04与18F-FDG的比较。

IF 0.9 4区医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Hellenic journal of nuclear medicine Pub Date : 2023-01-01 DOI:10.1967/s002449912559

Wei Zhang, Wei Diao, Zhuzhong Cheng

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引用次数: 0

摘要

近年来，放射性核素标记成纤维细胞激活蛋白抑制剂(FAPI)被认为是各种肿瘤最有前途的成像示踪剂。本文报道了食管癌术后复发患者中氟化铝(Al18F)标记的1,4,7-三氮杂环壬烷-N,N'，N"-三乙酸(Al18F- nota - fapi -04)和氟-18-氟脱氧葡萄糖(18F- fdg)的影像学表现。结果显示，与18F-FDG相比，Al18F-NOTA-FAPI-04成像对局部复发和远处转移的检测有显著提高，病变的最大标准化摄取值(SUVmax)更高。

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Comparison of Al ¹⁸F-NOTA-FAPI-04 and ¹⁸F-FDG in recurrent esophageal cancer after surgery.

Recently, radionuclide labelling fibroblast activating protein inhibitors (FAPI) is regarded as the most promising imaging tracer forvarious tumours. Here we present the imaging finding of aluminium-[¹⁸F] fluoride (Al¹⁸F)-labelled 1,4,7-triazacyclononane-N,N',N"-triacetic acid (Al¹⁸F-NOTA-FAPI-04) and fluorine-18-fluorodeoxyglucose (¹⁸F-FDG) in postoperative recurrence esophageal cancer. The results presented that imaging with Al¹⁸F-NOTA-FAPI-04 showed significant improvement in detection of local recurrence and distant metastasis with higher maximum standardized uptake value (SUVmax) in the lesions compared with ¹⁸F-FDG.

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来源期刊

Hellenic journal of nuclear medicine 医学-核医学

CiteScore

1.40

自引率

6.70%

发文量

审稿时长

>12 weeks

期刊介绍： The Hellenic Journal of Nuclear Medicine published by the Hellenic Society of Nuclear Medicine in Thessaloniki, aims to contribute to research, to education and cover the scientific and professional interests of physicians, in the field of nuclear medicine and in medicine in general. The journal may publish papers of nuclear medicine and also papers that refer to related subjects as dosimetry, computer science, targeting of gene expression, radioimmunoassay, radiation protection, biology, cell trafficking, related historical brief reviews and other related subjects. Original papers are preferred. The journal may after special agreement publish supplements covering important subjects, dully reviewed and subscripted separately.