在COVID-19大流行期间,布鲁克林中部1型和2型糖尿病住院儿童的比例增加。

IF 1.3 Q3 PEDIATRICS
Assia Miller, Shalu Joseph, Ahmed Badran, Vatcharapan Umpaichitra, Renee Bargman, Vivian L Chin
{"title":"在COVID-19大流行期间,布鲁克林中部1型和2型糖尿病住院儿童的比例增加。","authors":"Assia Miller,&nbsp;Shalu Joseph,&nbsp;Ahmed Badran,&nbsp;Vatcharapan Umpaichitra,&nbsp;Renee Bargman,&nbsp;Vivian L Chin","doi":"10.1155/2023/4580809","DOIUrl":null,"url":null,"abstract":"<p><p>Following reports of increased new-onset diabetes and worse severity of DKA for children with diabetes following SARS-CoV-2 infection, we studied hospitalization rates for children with type 1 diabetes (T1DM) and type 2 diabetes (T2DM) in our center during the citywide shutdown. <i>Methods</i>. We conducted a retrospective chart review of children admitted to our two hospitals from January 1, 2018, to December 31, 2020. We included ICD-10 codes for diabetic ketoacidosis (DKA), hyperglycemic hyperosmolar syndrome (HHS), and hyperglycemia only. <i>Results</i>. We included 132 patients with 214 hospitalizations: 157 T1DM, 41 T2DM, and 16 others (14 steroid induced, 2 MODY). Overall admissions rates for patients with all types of diabetes were 3.08% in 2018 to 3.54% in 2019 (<i>p</i> = 0.0120) and 4.73% in 2020 (<i>p</i> = 0.0772). Although there was no increase of T1DM admissions across all 3 years, T2DM admission rates increased from 0.29% to 1.47% (<i>p</i> = 0.0056). Newly diagnosed T1DM rates increased from 0.34% in 2018 to 1.28% (<i>p</i> = 0.002) in 2020, and new-onset T2DM rates also increased from 0.14% in 2018 to 0.9% in 2020 (<i>p</i> = 0.0012). Rates of new-onset diabetes presenting with DKA increased from 0.24% in 2018 to 0.96% in 2020 (<i>p</i> = 0.0014). HHS increased from 0.1% in 2018 to 0.45% in 2020 (<i>p</i> = 0.044). The severity of DKA in newly diagnosed was unaffected (<i>p</i> = 0.1582). Only 3 patients tested positive for SARS-CoV-2 infection by PCR. <i>Conclusion</i>. Our urban medical center is located in Central Brooklyn and serves a majority who are Black. This is the first study investigating pediatric diabetes cases admitted to Brooklyn during the first wave of the pandemic. Despite the overall pediatric admissions declining in 2020 due to the citywide shutdown, overall hospitalization rates in children with T2DM and in new-onset T1DM and T2DM increased, which is not directly associated with active SARS-CoV-2 infection. More studies are needed to elucidate the reason for this observed increase in hospitalization rates.</p>","PeriodicalId":51591,"journal":{"name":"International Journal of Pediatrics","volume":null,"pages":null},"PeriodicalIF":1.3000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10125760/pdf/","citationCount":"1","resultStr":"{\"title\":\"Increased Rates of Hospitalized Children with Type 1 and Type 2 Diabetes Mellitus in Central Brooklyn during the COVID-19 Pandemic.\",\"authors\":\"Assia Miller,&nbsp;Shalu Joseph,&nbsp;Ahmed Badran,&nbsp;Vatcharapan Umpaichitra,&nbsp;Renee Bargman,&nbsp;Vivian L Chin\",\"doi\":\"10.1155/2023/4580809\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Following reports of increased new-onset diabetes and worse severity of DKA for children with diabetes following SARS-CoV-2 infection, we studied hospitalization rates for children with type 1 diabetes (T1DM) and type 2 diabetes (T2DM) in our center during the citywide shutdown. <i>Methods</i>. We conducted a retrospective chart review of children admitted to our two hospitals from January 1, 2018, to December 31, 2020. We included ICD-10 codes for diabetic ketoacidosis (DKA), hyperglycemic hyperosmolar syndrome (HHS), and hyperglycemia only. <i>Results</i>. We included 132 patients with 214 hospitalizations: 157 T1DM, 41 T2DM, and 16 others (14 steroid induced, 2 MODY). Overall admissions rates for patients with all types of diabetes were 3.08% in 2018 to 3.54% in 2019 (<i>p</i> = 0.0120) and 4.73% in 2020 (<i>p</i> = 0.0772). Although there was no increase of T1DM admissions across all 3 years, T2DM admission rates increased from 0.29% to 1.47% (<i>p</i> = 0.0056). Newly diagnosed T1DM rates increased from 0.34% in 2018 to 1.28% (<i>p</i> = 0.002) in 2020, and new-onset T2DM rates also increased from 0.14% in 2018 to 0.9% in 2020 (<i>p</i> = 0.0012). Rates of new-onset diabetes presenting with DKA increased from 0.24% in 2018 to 0.96% in 2020 (<i>p</i> = 0.0014). HHS increased from 0.1% in 2018 to 0.45% in 2020 (<i>p</i> = 0.044). The severity of DKA in newly diagnosed was unaffected (<i>p</i> = 0.1582). Only 3 patients tested positive for SARS-CoV-2 infection by PCR. <i>Conclusion</i>. Our urban medical center is located in Central Brooklyn and serves a majority who are Black. This is the first study investigating pediatric diabetes cases admitted to Brooklyn during the first wave of the pandemic. Despite the overall pediatric admissions declining in 2020 due to the citywide shutdown, overall hospitalization rates in children with T2DM and in new-onset T1DM and T2DM increased, which is not directly associated with active SARS-CoV-2 infection. More studies are needed to elucidate the reason for this observed increase in hospitalization rates.</p>\",\"PeriodicalId\":51591,\"journal\":{\"name\":\"International Journal of Pediatrics\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10125760/pdf/\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Pediatrics\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1155/2023/4580809\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"PEDIATRICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Pediatrics","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1155/2023/4580809","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PEDIATRICS","Score":null,"Total":0}
引用次数: 1

摘要

在SARS-CoV-2感染后糖尿病儿童新发糖尿病增加和DKA严重程度加重的报告之后,我们研究了全市范围内关闭期间我中心1型糖尿病(T1DM)和2型糖尿病(T2DM)儿童的住院率。方法。我们对2018年1月1日至2020年12月31日在两家医院住院的儿童进行了回顾性图表回顾。我们纳入了糖尿病酮症酸中毒(DKA)、高血糖性高渗综合征(HHS)和高血糖症的ICD-10编码。结果。我们纳入了214例住院的132例患者:157例为T1DM, 41例为T2DM, 16例为其他(14例为类固醇诱导,2例为MODY)。所有类型糖尿病患者的总体住院率在2018年为3.08%,2019年为3.54% (p = 0.0120), 2020年为4.73% (p = 0.0772)。虽然在所有3年中,T2DM的入院率没有增加,但T2DM的入院率从0.29%增加到1.47% (p = 0.0056)。新发T2DM率从2018年的0.34%上升到2020年的1.28% (p = 0.002),新发T2DM率也从2018年的0.14%上升到2020年的0.9% (p = 0.0012)。新发糖尿病合并DKA的比例从2018年的0.24%上升到2020年的0.96% (p = 0.0014)。HHS从2018年的0.1%上升到2020年的0.45% (p = 0.044)。新诊断DKA的严重程度不受影响(p = 0.1582)。仅有3例患者经PCR检测为SARS-CoV-2感染阳性。结论。我们的城市医疗中心位于布鲁克林中部,主要为黑人服务。这是对第一波大流行期间布鲁克林收治的儿科糖尿病病例进行调查的第一项研究。尽管由于全市范围的关闭,2020年儿科住院总人数有所下降,但T2DM儿童以及新发T1DM和T2DM的总体住院率有所上升,这与活跃的SARS-CoV-2感染没有直接关系。需要更多的研究来阐明观察到的住院率增加的原因。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Increased Rates of Hospitalized Children with Type 1 and Type 2 Diabetes Mellitus in Central Brooklyn during the COVID-19 Pandemic.

Following reports of increased new-onset diabetes and worse severity of DKA for children with diabetes following SARS-CoV-2 infection, we studied hospitalization rates for children with type 1 diabetes (T1DM) and type 2 diabetes (T2DM) in our center during the citywide shutdown. Methods. We conducted a retrospective chart review of children admitted to our two hospitals from January 1, 2018, to December 31, 2020. We included ICD-10 codes for diabetic ketoacidosis (DKA), hyperglycemic hyperosmolar syndrome (HHS), and hyperglycemia only. Results. We included 132 patients with 214 hospitalizations: 157 T1DM, 41 T2DM, and 16 others (14 steroid induced, 2 MODY). Overall admissions rates for patients with all types of diabetes were 3.08% in 2018 to 3.54% in 2019 (p = 0.0120) and 4.73% in 2020 (p = 0.0772). Although there was no increase of T1DM admissions across all 3 years, T2DM admission rates increased from 0.29% to 1.47% (p = 0.0056). Newly diagnosed T1DM rates increased from 0.34% in 2018 to 1.28% (p = 0.002) in 2020, and new-onset T2DM rates also increased from 0.14% in 2018 to 0.9% in 2020 (p = 0.0012). Rates of new-onset diabetes presenting with DKA increased from 0.24% in 2018 to 0.96% in 2020 (p = 0.0014). HHS increased from 0.1% in 2018 to 0.45% in 2020 (p = 0.044). The severity of DKA in newly diagnosed was unaffected (p = 0.1582). Only 3 patients tested positive for SARS-CoV-2 infection by PCR. Conclusion. Our urban medical center is located in Central Brooklyn and serves a majority who are Black. This is the first study investigating pediatric diabetes cases admitted to Brooklyn during the first wave of the pandemic. Despite the overall pediatric admissions declining in 2020 due to the citywide shutdown, overall hospitalization rates in children with T2DM and in new-onset T1DM and T2DM increased, which is not directly associated with active SARS-CoV-2 infection. More studies are needed to elucidate the reason for this observed increase in hospitalization rates.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
3.90
自引率
0.00%
发文量
0
审稿时长
4 weeks
期刊介绍: International Journal of Pediatrics is a peer-reviewed, open access journal that publishes original researcharticles, review articles, and clinical studies in all areas of pediatric research. The journal accepts submissions presented as an original article, short communication, case report, review article, systematic review, or letter to the editor.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信