Later-Life Functionality in Married Women: The Mediating Role of Self-Perpetuating BMI and Pain Trajectories.

The current study investigated how pain and BMI trajectories mediate the influence of family stress (1991-1994) on later-life impaired functionality (2017) in women. The study used prospective data from 244 mid-older rural Midwest Caucasian women who were in long-term marriages over a span of 27 years. Within the structural equation framework, the analytical model used latent constructs of family stress and trajectories of pain and BMI to predict later-life functionality. BMI and pain trajectories mutually influenced each other in forming a self-perpetuating cycle over time in mid-older women. Further, midlife family stress shaped BMI and pain trajectories, and these trajectories had consequences for later-life functionality, as defined by three kinds of impairments: physical, cognitive (subjective memory), and social (loneliness). The findings emphasize the need for policies and interventions that focus on reducing women's stressful family circumstances in middle years to weaken and redirect their association with BMI and pain trajectories.