执行功能发展的相关因素:累积多巴胺遗传评分和环境因素预测幼儿园儿童在go/nogo任务中的表现

IF 3.4 Q2 NEUROSCIENCES
Marie Fiedler , Carmen Hofmann , Christian Montag , Markus Kiefer
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引用次数: 0

摘要

背景本研究旨在探讨遗传和环境因素在预测四至六岁儿童执行功能方面的相互作用。方法采用go/nogo任务对197名儿童的反应抑制作为EF指标进行评估。计算累积多巴胺(DA)遗传评分,为低DA活性的易感性提供指标。对父母行为和父母教育的维度进行了评估。结果父母教育与nogo试验的准确性呈正相关。累积遗传得分和父母维度反应性之间的相互作用预测了go RT,表明具有高累积遗传分数和高父母反应性的儿童表现出谨慎的反应模式。结论幼儿园儿童EF的发生与父母教育有关,也与DA系统的分子遗传学与父母行为之间的相互作用有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Factors related to the development of executive functions: A cumulative dopamine genetic score and environmental factors predict performance of kindergarten children in a go/nogo task

Background

This study aimed at investigating the interaction between genetic and environmental factors in predicting executive function in children aged four to six years.

Methods

Response inhibition as index of EF was assessed in 197 children using a go/nogo task. A cumulative dopamine (DA) genetic score was calculated, indexing predisposition of low DA activity. Dimensions of parenting behavior and parental education were assessed.

Results

Parental education was positively related to accuracy in nogo trials. An interaction between the cumulative genetic score and the parenting dimension Responsiveness predicted go RT indicating that children with a high cumulative genetic score and high parental responsiveness exhibited a careful response mode.

Conclusion

The development of EF in kindergarten children is related to parental education as well as to an interaction between the molecular-genetics of the DA system and parenting behavior.

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来源期刊
CiteScore
6.30
自引率
6.10%
发文量
22
审稿时长
65 days
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