{"title":"生活质量:头颈癌治疗成功与否的决定因素:生存与康复之争。","authors":"Mahathi Neralla, Sudarssan Subramaniam Gouthaman, Senthilnathan P, Tharini Satheesh, Ravalika Singarapu","doi":"10.23736/S2724-6329.23.04722-8","DOIUrl":null,"url":null,"abstract":"<p><strong>Backgound: </strong>Surgical treatment for cancers in the oral and maxillofacial region significantly impacts a patient's physical, social, functional, and psychological well-being, which can in-turn affect the Quality of Life (QoL) negatively. The goal of our study was to assess the Quality of Life (QoL) of patients who underwent surgery in our hospital, and we attempted to extrapolate the data which could in the future help improve the QoL of other patients who undergo similar treatments.</p><p><strong>Methods: </strong>This was a retrospective study, including patients who have been treated for oral cancer in the last few years in the institute. The standard EORTC Questionnaires QLQ C-30 (version 3.0) and QLQ H and N-35 (version 1.0) were used in this study.</p><p><strong>Results: </strong>GHS scores were lower in patients with T3 stage tumor than in patients with T1 stage tumor. Patients who underwent surgery along with radiotherapy and those who underwent surgery, radiotherapy, and chemotherapy showed a substantial difference in their GHS and FS ratings when their treatment options were compared. Patients who had undergone surgery, radiation, and chemotherapy had higher scores on the symptom scale and QoL H&N-35 than patients who had just undergone surgery and radiotherapy There was no statistically significant difference in the scores, pertaining to the location, age, gender and stage of the tumor but when the comparison was made on the basis of treatment modality chosen, there was a significant difference in the scores.</p><p><strong>Conclusions: </strong>The aim of any treatment is to improve the Quality of Life. The EORTC questionnaires QLQ 30 and QLQ H and N-35 proved to be very appropriate instruments to evaluate QoL in patients with oral cancer. Assessment of QoL should always receive adequate attention in treatment planning and rehabilitation. Choice of treatment modality plays a significant role in QoL of patients treated for oral cancer. Henceforth, any treatment modality should be selected not only with a curative intent but also with the goal of improving the Quality of Life as this ultimately decides the success of the therapy from the patient's perspective.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":null,"pages":null},"PeriodicalIF":1.1000,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Quality of Life: determinant of success of head and neck cancer therapy in the battle of survival vs. rehabilitation.\",\"authors\":\"Mahathi Neralla, Sudarssan Subramaniam Gouthaman, Senthilnathan P, Tharini Satheesh, Ravalika Singarapu\",\"doi\":\"10.23736/S2724-6329.23.04722-8\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Backgound: </strong>Surgical treatment for cancers in the oral and maxillofacial region significantly impacts a patient's physical, social, functional, and psychological well-being, which can in-turn affect the Quality of Life (QoL) negatively. The goal of our study was to assess the Quality of Life (QoL) of patients who underwent surgery in our hospital, and we attempted to extrapolate the data which could in the future help improve the QoL of other patients who undergo similar treatments.</p><p><strong>Methods: </strong>This was a retrospective study, including patients who have been treated for oral cancer in the last few years in the institute. The standard EORTC Questionnaires QLQ C-30 (version 3.0) and QLQ H and N-35 (version 1.0) were used in this study.</p><p><strong>Results: </strong>GHS scores were lower in patients with T3 stage tumor than in patients with T1 stage tumor. Patients who underwent surgery along with radiotherapy and those who underwent surgery, radiotherapy, and chemotherapy showed a substantial difference in their GHS and FS ratings when their treatment options were compared. Patients who had undergone surgery, radiation, and chemotherapy had higher scores on the symptom scale and QoL H&N-35 than patients who had just undergone surgery and radiotherapy There was no statistically significant difference in the scores, pertaining to the location, age, gender and stage of the tumor but when the comparison was made on the basis of treatment modality chosen, there was a significant difference in the scores.</p><p><strong>Conclusions: </strong>The aim of any treatment is to improve the Quality of Life. The EORTC questionnaires QLQ 30 and QLQ H and N-35 proved to be very appropriate instruments to evaluate QoL in patients with oral cancer. Assessment of QoL should always receive adequate attention in treatment planning and rehabilitation. Choice of treatment modality plays a significant role in QoL of patients treated for oral cancer. Henceforth, any treatment modality should be selected not only with a curative intent but also with the goal of improving the Quality of Life as this ultimately decides the success of the therapy from the patient's perspective.</p>\",\"PeriodicalId\":18709,\"journal\":{\"name\":\"Minerva dental and oral science\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.1000,\"publicationDate\":\"2023-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Minerva dental and oral science\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.23736/S2724-6329.23.04722-8\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2023/4/17 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Minerva dental and oral science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.23736/S2724-6329.23.04722-8","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/4/17 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
引用次数: 0
摘要
背景:口腔颌面部癌症的手术治疗会对患者的身体、社交、功能和心理健康产生重大影响,进而对生活质量(QoL)产生负面影响。我们的研究目标是评估在本院接受手术的患者的生活质量(QoL),并试图推断出这些数据,从而在未来帮助其他接受类似治疗的患者提高生活质量:这是一项回顾性研究,包括过去几年在本院接受口腔癌治疗的患者。研究使用了标准的 EORTC 问卷 QLQ C-30(3.0 版)和 QLQ H 和 N-35(1.0 版):T3期肿瘤患者的GHS评分低于T1期肿瘤患者。在比较治疗方案时,接受手术和放疗的患者与接受手术、放疗和化疗的患者在 GHS 和 FS 评分上有很大差异。与只接受手术和放疗的患者相比,接受手术、放疗和化疗的患者在症状量表和 QoL H&N-35 评分上更高。在肿瘤的位置、年龄、性别和分期方面,评分没有统计学意义上的显著差异,但在选择治疗方式的基础上进行比较时,评分有显著差异:结论:任何治疗的目的都是为了提高生活质量。事实证明,EORTC QLQ 30 和 QLQ H 及 N-35 问卷是评估口腔癌患者生活质量的非常合适的工具。在治疗计划和康复过程中,应始终充分重视对 QoL 的评估。治疗方式的选择对口腔癌患者的 QoL 起着重要作用。因此,在选择任何治疗方式时,不仅要以治愈为目的,还要以提高生活质量为目标,因为从患者的角度来看,这最终决定了治疗的成功与否。
Quality of Life: determinant of success of head and neck cancer therapy in the battle of survival vs. rehabilitation.
Backgound: Surgical treatment for cancers in the oral and maxillofacial region significantly impacts a patient's physical, social, functional, and psychological well-being, which can in-turn affect the Quality of Life (QoL) negatively. The goal of our study was to assess the Quality of Life (QoL) of patients who underwent surgery in our hospital, and we attempted to extrapolate the data which could in the future help improve the QoL of other patients who undergo similar treatments.
Methods: This was a retrospective study, including patients who have been treated for oral cancer in the last few years in the institute. The standard EORTC Questionnaires QLQ C-30 (version 3.0) and QLQ H and N-35 (version 1.0) were used in this study.
Results: GHS scores were lower in patients with T3 stage tumor than in patients with T1 stage tumor. Patients who underwent surgery along with radiotherapy and those who underwent surgery, radiotherapy, and chemotherapy showed a substantial difference in their GHS and FS ratings when their treatment options were compared. Patients who had undergone surgery, radiation, and chemotherapy had higher scores on the symptom scale and QoL H&N-35 than patients who had just undergone surgery and radiotherapy There was no statistically significant difference in the scores, pertaining to the location, age, gender and stage of the tumor but when the comparison was made on the basis of treatment modality chosen, there was a significant difference in the scores.
Conclusions: The aim of any treatment is to improve the Quality of Life. The EORTC questionnaires QLQ 30 and QLQ H and N-35 proved to be very appropriate instruments to evaluate QoL in patients with oral cancer. Assessment of QoL should always receive adequate attention in treatment planning and rehabilitation. Choice of treatment modality plays a significant role in QoL of patients treated for oral cancer. Henceforth, any treatment modality should be selected not only with a curative intent but also with the goal of improving the Quality of Life as this ultimately decides the success of the therapy from the patient's perspective.