确定未成熟粒细胞百分比和全身免疫炎症指数预测急性肾盂肾炎的有效性。

IF 2.6 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Deniz Karakaya, Tülin Güngör, Evrim Kargın Cakıcı, Fatma Yazılıtaş, Evra Celikkaya, Mehmet Bulbul
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引用次数: 1

摘要

目的:尿路感染(UTI)最严重的形式是急性肾盂肾炎(APN),它可导致菌血症和肾瘢痕。本研究旨在通过与传统感染标志物的比较,揭示全身免疫炎症指数(SII)和未成熟粒细胞(IG)百分比在预测儿科患者APN中的作用。通过说明APN、IG百分比和SII之间的显著关系,该研究对UTI的鉴别诊断的贡献可以促进APN的快速和适当治疗。材料和方法:本研究纳入522例儿科患者。患者分为两组:(I) APN组(n = 236)和(II)低UTI组(n = 286)。结果:患者平均年龄5.05±4.7岁。根据最合适的截止值,研究结果显示,在所有参数中,c反应蛋白(CRP)和IG百分比对预测APN的敏感性、特异性和预测值最高。结论:本研究强调了IG百分比和SII在儿科APN诊断中的支持作用,这是近年来备受关注的课题。研究结果表明,在CRP背后的所有参数中,IG百分比和SII对预测APN具有最高的敏感性、特异性和预测值。值得注意的是,这些方法的应用不会给患者带来额外的费用或负担。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Determining the effectiveness of the immature granulocyte percentage and systemic immune-inflammation index in predicting acute pyelonephritis.

Aim: The most serious form of urinary tract infection (UTI) is acute pyelonephritis (APN), which can result in bacteremia and renal scarring. This study aims to show the roles that the systemic immune-inflammation index (SII) and the immature granulocyte (IG) percentage play in predicting APN in pediatric patients by comparing them with traditional infection markers. By illustrating a significant relationship between APN, the IG percentage, and the SII, the study's contributions to the differential diagnosis of UTI can promote a rapid and appropriate treatment of APN.

Material and methods: The present study included 522 pediatric patients. The patients were divided into two groups: (I) an APN group (n = 236) and (II) a lower UTI group (n = 286).

Results: The mean age of the sample was 5.05 ± 4.7 years. According to the most appropriate cutoff values, the findings showed that among all the parameters, C-reactive protein (CRP) and the IG percentage had the highest sensitivities, specificities, and predictive values for predicting APN.

Conclusion: This study emphasizes the support features of the IG percentage and the SII in the diagnosis of APN in pediatric patients, a topic that has recently attracted attention. The findings indicated that among all of the parameters behind CRP, the IG percentage and the SII had the highest sensitivities, specificities, and predictive values for forecasting APN. It is worth noting that these methods can be applied without additional costs or burdens to the patient.

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来源期刊
Postgraduate Medicine
Postgraduate Medicine 医学-医学:内科
CiteScore
6.10
自引率
2.40%
发文量
110
审稿时长
6-12 weeks
期刊介绍: Postgraduate Medicine is a rapid peer-reviewed medical journal published for physicians. Tracing its roots back to 1916,  Postgraduate Medicine  was established by Charles Mayo, MD, as a peer-to-peer method of communicating the latest research to aid physicians when making treatment decisions, and it maintains that aim to this day. In addition to its core subscriber base, Postgraduate Medicine is distributed to hundreds of US-based physicians within internal medicine and family practice.
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