乳酸菌外多糖作为抗生素的替代品对肠道健康和免疫系统的调节

IF 6.3
Shuo Yang, Xiaoqing Xu, Qing Peng, Lan Ma, Yu Qiao, Bo Shi
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引用次数: 9

摘要

在畜禽生产中过度使用或滥用抗生素导致动物对抗生素耐药性的威胁不断增加,并对生态产生负面影响。乳酸菌外多糖(LAB-EPS)是乳酸菌在生长和代谢过程中分泌到细胞壁外的一类生物大分子。大量研究表明,LAB-EPS具有抗炎和抗菌活性,能够调节牲畜的肠道健康和免疫系统。它们具有生物可降解、无毒和生物相容性,被认为是抗生素的理想替代品。本综述旨在讨论和总结LAB-EPS在动物肠道健康和免疫系统调节方面的最新研究成果,从而为LAB-EPS的商业应用提供科学依据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Exopolysaccharides from lactic acid bacteria, as an alternative to antibiotics, on regulation of intestinal health and the immune system

Exopolysaccharides from lactic acid bacteria, as an alternative to antibiotics, on regulation of intestinal health and the immune system

Over-use or misuse of antibiotics in livestock and poultry production contributes to the rising threat of antibiotic resistance in animals and has negative ecological effects. Exopolysaccharides from lactic acid bacteria (LAB-EPS) are a class of biological macromolecules which are secreted by lactic acid bacteria to the outside of the cell wall during their growth and metabolism. Numerous studies demonstrated that LAB-EPS have anti-inflammatory and antimicrobial activities and are able to regulate intestinal health and the immune system in livestock. They are biodegradable, nontoxic and bio-compatible, which are considered as ideal alternatives to antibiotics. This review aims to discuss and summarize recent research findings of LAB-EPS on regulation of intestinal health and the immune system in animals, and thus provide scientific justification for commercial applications of LAB-EPS in livestock.

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来源期刊
Animal Nutrition
Animal Nutrition Animal Science and Zoology
CiteScore
9.70
自引率
0.00%
发文量
542
审稿时长
65 days
期刊介绍: Animal Nutrition encompasses the full gamut of animal nutritional sciences and reviews including, but not limited to, fundamental aspects of animal nutrition such as nutritional requirements, metabolic studies, body composition, energetics, immunology, neuroscience, microbiology, genetics and molecular and cell biology related to primarily to the nutrition of farm animals and aquatic species. More applied aspects of animal nutrition, such as the evaluation of novel ingredients, feed additives and feed safety will also be considered but it is expected that such studies will have a strong nutritional focus. Animal Nutrition is indexed in SCIE, PubMed Central, Scopus, DOAJ, etc.
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