短期使用生物遏制气泡:潜在传染性SARS-CoV-2气溶胶的创新源头遏制。

IF 0.5 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Applied Biosafety Pub Date : 2022-12-01 Epub Date: 2022-11-23 DOI:10.1089/apb.2022.0010
Benjamin Fontes, Tessa Landgraf, Jeremy Stoddard, Neil Velasquez
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引用次数: 0

摘要

简介:本文将回顾用于开发简单有效的密封工程控制的过程。耶鲁大学称其为“耶鲁生物遏制气泡”(STUBB-Ys),其设计、制造、测试和实施是为了保护耶鲁大学社区成员免受SARS-CoV-2气溶胶的影响。stubb - y是与最终用户共同设计和创建的,由环境健康与安全(EHS)或合作伙伴团队建造,并在安装后进行现场测试,以验证有效的操作和密封。方法:开发和安装了各种不同设置的设备。STUBB-Ys用于COVID-19室内测试中心、实验室和诊所。这些装置是为了在现有程序不能利用或不充分的情况下制定预防感染的措施。每个STUBB-Y都使用C-Breeze冷凝湿度气流可视化仪和Fluke 985颗粒计数器进行测试,该计数器可以提供0.3至10 μm的颗粒计数,以直观和定量地测量颗粒逃逸。在适用的情况下,还使用TSI VelociCalc 9525风速计测试了气流速率。结果:通过添加这些简单的密封装置来限制气溶胶,学生和教师能够安全地在目标区域继续进行重要的研究或临床研究。结论:从生物风险管理的角度来看,EHS能够使用简单的设计和设备并坚持控制层次,将气溶胶限制在其潜在来源。本文演示了如何使用简单的设计过程来加强大流行期间的工人保护。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Short-Term Use Biocontainment Bubbles: Innovative Source Containment of Potentially Infectious SARS-CoV-2 Aerosols.

Introduction: This article will review the processes utilized to develop simple effective containment engineering controls. Short-Term Use Biocontainment Bubbles-Yale (STUBB-Ys), as Yale refers to them, were designed, built, tested, and implemented to protect members of the Yale University community from exposure to SARS-CoV-2 aerosols. STUBB-Ys were designed and created in conjunction with end users, constructed by Environmental Health and Safety (EHS) or partner groups, and tested onsite after installation to verify effective operation and containment.

Methods: A wide variety of devices in different settings were developed and installed. STUBB-Ys were used at COVID-19 indoor test centers, laboratories, and clinics. The devices were pursued to create infection prevention measures where existing processes could not be utilized or were inadequate. Each STUBB-Y was tested with a C-Breeze Condensed Moisture Airflow Visualizer to generate smoke and a Fluke 985 Particle Counter, which gives the particle counts from 0.3 to 10 μm to measure particle escape visually and quantitatively. Airflow rates were also tested where applicable with a TSI VelociCalc 9525 Air Velocity Meter.

Results: Students and faculty were able to safely continue vital research or clinical study in the targeted areas with the addition of these simple containment devices to confine aerosols.

Conclusion: From a biorisk management point of view, EHS was able to confine aerosols at their potential source using simple designs and equipment and adhering to the hierarchy of controls. This article demonstrates how a straightforward design process can be used to enhance worker protection during a pandemic.

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来源期刊
Applied Biosafety
Applied Biosafety Environmental Science-Management, Monitoring, Policy and Law
CiteScore
2.50
自引率
13.30%
发文量
27
期刊介绍: Applied Biosafety (APB), sponsored by ABSA International, is a peer-reviewed, scientific journal committed to promoting global biosafety awareness and best practices to prevent occupational exposures and adverse environmental impacts related to biohazardous releases. APB provides a forum for exchanging sound biosafety and biosecurity initiatives by publishing original articles, review articles, letters to the editors, commentaries, and brief reviews. APB informs scientists, safety professionals, policymakers, engineers, architects, and governmental organizations. The journal is committed to publishing on topics significant in well-resourced countries as well as information relevant to underserved regions, engaging and cultivating the development of biosafety professionals globally.
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