多发性硬化症的认知缺陷：听觉和视觉注意及抑制控制。

IF 1.4 4区心理学 Q4 CLINICAL NEUROLOGY

Applied Neuropsychology-Adult Pub Date : 2025-03-01 Epub Date: 2023-03-27 DOI:10.1080/23279095.2023.2192408

Leila Simani, Mahrooz Roozbeh, Maziyar Shojaei, Mohammad Rostami, Mehrdad Roozbeh, Mohammad Ali Sahraian

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引用次数: 0

摘要

背景：越来越多的证据表明多发性硬化症（MS）患者的认知功能受损。然而，关于MS认知功能的研究也产生了相互矛盾的结果。本研究探讨多发性硬化症患者的注意力和抑制控制功能及其与患者抑郁、疲劳等其他临床特征的关系。方法：参与者包括80例多发性硬化症患者和60例健康对照者。采用综合视听连续表现测验（IVA-CPT）、疲劳严重程度量表（FSS）和医院焦虑抑郁量表（HADS）对所有受试者的注意力和抑制控制、疲劳和精神筛查进行研究。结果：多发性硬化症患者在IVA-CPT任务中的表现比健康对照组差(p)。结论：多发性硬化症患者的抑制控制和注意力明显受损。

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Cognitive deficits in multiple sclerosis: Auditory and visual attention and inhibitory control.

Background: A growing body of evidence has been paid to the cognitive impairment in patients with multiple sclerosis (MS). However, studies concerning cognitive functions in MS have also yielded conflicting results. This study investigates the attention and inhibitory control functions in patients with MS and their relationship with other clinical features, such as depression and fatigue in these patients.

Methods: Participants included 80 patients with MS and 60 healthy controls. The attention and inhibitory control, fatigue, and psychiatric screening in all subjects were studied, respectively with the Integrated Visual and Auditory Continuous Performance Test (IVA-CPT), Fatigue Severity Scale (FSS), and the Hospital Anxiety and Depression Scale (HADS).

Results: Patients with MS performed the IVA-CPT task more poorly than the healthy control group (p < 0.001). However, multiple regression analysis did not show any significant relationship between disease duration, FSS, and HADS on attention and inhibitory control.

Conclusion: Inhibitory control and attention are significantly impaired in patients with MS. Finding the basics of cognitive deficits in MS have potentially important clinical implications for developing better cognitive rehabilitation strategies.

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来源期刊

Applied Neuropsychology-Adult CLINICAL NEUROLOGY-PSYCHOLOGY

CiteScore

4.50

自引率

11.80%

发文量

134

期刊介绍： pplied Neuropsychology-Adult publishes clinical neuropsychological articles concerning assessment, brain functioning and neuroimaging, neuropsychological treatment, and rehabilitation in adults. Full-length articles and brief communications are included. Case studies of adult patients carefully assessing the nature, course, or treatment of clinical neuropsychological dysfunctions in the context of scientific literature, are suitable. Review manuscripts addressing critical issues are encouraged. Preference is given to papers of clinical relevance to others in the field. All submitted manuscripts are subject to initial appraisal by the Editor-in-Chief, and, if found suitable for further considerations are peer reviewed by independent, anonymous expert referees. All peer review is single-blind and submission is online via ScholarOne Manuscripts.