SARS-CoV-2组粒变异在“动态零”期间的发病率小幅上升。

IF 2.6 4区 医学 Q3 INFECTIOUS DISEASES
Xiaona Li, Ruili Li, Qiguo Lian, Yang Wang, Wenkui Gu, Qinghe Meng
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引用次数: 1

摘要

为描述“动态零”期间SARS-CoV-2基因组变异的流行病学特征和传播动态,我们分析了2022年5月14日至30日天津市北辰区108例实验室确诊的SARS-CoV-2病例资料。我们收集了108例病例的人口学特征、暴露史和发病时间。我们描述了患者的特征,并估计了关键的流行病学参数,包括序列间隔和随时间变化的Omicron变异繁殖数,rt。在108例实验室确诊患者中,中位年龄为38岁,50.9%为女性。67.6%(73/108)的病例出现明显症状,主要临床表现为发热、喉咙痛和咳嗽,分别占31.5%、26.9%和19.4%。SI的平均值和标准差估计为2.89和0.95天,在7天的时间间隔内,Rt从1.24到0.27不等。低繁殖数量和短时间内抑制欧米克隆疫情标志着实施的公共卫生措施的有效性,如核酸筛查、社会距离、口罩、疫苗接种、患者医疗和密切接触者隔离。这些措施在实现控制疾病传播的目标方面发挥了重要作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

A Small Surge in Incidence of SARS-CoV-2 Omicron Variant in the "Dynamic Zero" Period.

A Small Surge in Incidence of SARS-CoV-2 Omicron Variant in the "Dynamic Zero" Period.

To describe the epidemiological characteristics and transmission dynamics of SARS-CoV-2 Omicron variant during "Dynamic Zero" period, we analyzed data on the 108 laboratory-confirmed SARS-CoV-2 cases during 14 to 30 May 2022 in Beichen district, Tianjin, China. We collected information on demographic characteristics, exposure history, and illness timelines of the 108 cases. We described characteristics of the patients and estimated the key epidemiological parameters, including serial interval and the time-dependent reproduction number of the Omicron variant, Rt. Among the 108 laboratory-confirmed patients, the median age was 38 years old, and 50.9% were females. Obvious symptoms were observed among 67.6% (73/108) of all cases, and major clinical manifestations included fever, sore throat, and cough, which occurred in 31.5%, 26.9%, and 19.4% of the 108 cases, respectively. The mean and standard deviation of the SI were estimated as 2.89 and 0.95 days, the Rt varied from 1.24 to 0.27 for a 7-day timelapse. The low reproduction number and the Omicron outbreak being suppressed within a short time marked the effectiveness of the implemented public health measures, such as nucleic acid screening, social distancing, masking, vaccination, medical treatment of patients, and isolation of close contacts. These measures play an important role in fulfilling the goal of controlling the spread of the disease.

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来源期刊
CiteScore
4.30
自引率
0.00%
发文量
108
审稿时长
>12 weeks
期刊介绍: Canadian Journal of Infectious Diseases and Medical Microbiology is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies related to infectious diseases of bacterial, viral and parasitic origin. The journal welcomes articles describing research on pathogenesis, epidemiology of infection, diagnosis and treatment, antibiotics and resistance, and immunology.
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