Guang-Li Zhang, Tian-Yi Sun, Sen Li, Man-Xi Jiang, Lei Guo
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引用次数: 0
摘要
目的:比较第5天劣质囊胚和第6天优质囊胚单周期移植的效果。方法:对2014年1月至2019年12月在我中心进行的462例冻融胚胎移植(FET)周期进行分析。周期分为两组:第5天劣质囊胚移植组(a组)和第6天优质囊胚移植组(B组)，检测临床结果。结果:A、B组临床妊娠率(CPR;61.65% vs. 67.17%， p=0.258)，着床率(IR;61.65% vs. 67.17%， p=0.258)，活产率(LBR;69.51% vs. 77.83% (p=0.134)，差异无统计学意义。考虑第3天胚胎质量时，A组和B组的CPR、IR和LBR相似(p>0.05)。结论:第5天劣质囊胚与第6天优质囊胚的临床结果相似，提示胚胎发育速度可能比胚胎质量对FET周期单个囊胚移植的临床结果更重要。
The pregnancy outcomes of day-5 poor-quality and day-6 high-quality blastocysts in single blastocyst transfer cycles.
Objective: This study compared the outcomes of single blastocyst transfer cycles, using day- 5 poor-quality blastocysts and day-6 high-quality blastocysts.
Methods: We analyzed 462 frozen-thawed embryo transfer (FET) cycles performed at our center from January 2014 to December 2019. The cycles were divided into two groups: a day-5 poor-quality blastocyst transfer group (group A) and a day-6 high-quality blastocyst transfer group (group B). The clinical outcomes were tested.
Results: In groups A and B, respectively, the clinical pregnancy rate (CPR; 61.65% vs. 67.17%, p=0.258), implantation rate (IR; 61.65% vs. 67.17%, p=0.258), and live birth rate (LBR; 69.51% vs. 77.83%, p=0.134) showed no significant differences. Moreover, when day-3 embryo quality was considered, the CPR, IR, and LBR were also similar in group A and group B (p>0.05).
Conclusion: The clinical outcomes of day-5 poor-quality blastocysts and day-6 high-quality blastocysts were similar, suggesting that the developmental speed of the embryo might be more important than embryo quality for the clinical outcomes of single blastocyst transfer in FET cycles.
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