{"title":"内皮细胞和血管平滑肌细胞中的肾上腺素能受体","authors":"Jessica Gambardella , Antonella Fiordelisi , Roberta Avvisato , Antonietta Buonaiuto , Federica A Cerasuolo , Daniela Sorriento , Guido Iaccarino","doi":"10.1016/j.cophys.2023.100721","DOIUrl":null,"url":null,"abstract":"<div><p>Adrenergic receptors (AR) are essential regulators of vascular physiology and are largely used as pharmacological targets. This chapter will review the main roles of the vascular AR in both the endothelium and vascular smooth muscle. We will discuss the ability of ARs to regulate key functions in endothelial and smooth muscle cells and their involvement in several pathologic conditions such as hypertension, atherosclerosis, and heart failure.</p></div>","PeriodicalId":52156,"journal":{"name":"Current Opinion in Physiology","volume":"36 ","pages":"Article 100721"},"PeriodicalIF":2.5000,"publicationDate":"2023-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Adrenergic receptors in endothelial and vascular smooth muscle cells\",\"authors\":\"Jessica Gambardella , Antonella Fiordelisi , Roberta Avvisato , Antonietta Buonaiuto , Federica A Cerasuolo , Daniela Sorriento , Guido Iaccarino\",\"doi\":\"10.1016/j.cophys.2023.100721\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Adrenergic receptors (AR) are essential regulators of vascular physiology and are largely used as pharmacological targets. This chapter will review the main roles of the vascular AR in both the endothelium and vascular smooth muscle. We will discuss the ability of ARs to regulate key functions in endothelial and smooth muscle cells and their involvement in several pathologic conditions such as hypertension, atherosclerosis, and heart failure.</p></div>\",\"PeriodicalId\":52156,\"journal\":{\"name\":\"Current Opinion in Physiology\",\"volume\":\"36 \",\"pages\":\"Article 100721\"},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2023-10-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current Opinion in Physiology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2468867323000925\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PHYSIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Opinion in Physiology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2468867323000925","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PHYSIOLOGY","Score":null,"Total":0}
Adrenergic receptors in endothelial and vascular smooth muscle cells
Adrenergic receptors (AR) are essential regulators of vascular physiology and are largely used as pharmacological targets. This chapter will review the main roles of the vascular AR in both the endothelium and vascular smooth muscle. We will discuss the ability of ARs to regulate key functions in endothelial and smooth muscle cells and their involvement in several pathologic conditions such as hypertension, atherosclerosis, and heart failure.
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