内皮细胞和血管平滑肌细胞中的肾上腺素能受体

IF 2.5 Q2 PHYSIOLOGY

Current Opinion in Physiology Pub Date : 2023-10-12 DOI:10.1016/j.cophys.2023.100721

Jessica Gambardella , Antonella Fiordelisi , Roberta Avvisato , Antonietta Buonaiuto , Federica A Cerasuolo , Daniela Sorriento , Guido Iaccarino

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引用次数: 0

摘要

肾上腺素能受体(AR)是血管生理的重要调节因子，被广泛用作药物靶点。本章将综述血管AR在内皮和血管平滑肌中的主要作用。我们将讨论ARs调节内皮细胞和平滑肌细胞关键功能的能力，以及它们在高血压、动脉粥样硬化和心力衰竭等几种病理状况中的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Adrenergic receptors in endothelial and vascular smooth muscle cells

Adrenergic receptors (AR) are essential regulators of vascular physiology and are largely used as pharmacological targets. This chapter will review the main roles of the vascular AR in both the endothelium and vascular smooth muscle. We will discuss the ability of ARs to regulate key functions in endothelial and smooth muscle cells and their involvement in several pathologic conditions such as hypertension, atherosclerosis, and heart failure.

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来源期刊

Current Opinion in Physiology Medicine-Physiology (medical)

CiteScore

5.80

自引率

0.00%

发文量