极端肿瘤成形术,乳房切除术的替代方案?本研究的目的是:

IF 0.2 Q4 OBSTETRICS & GYNECOLOGY
Mireia Gutiérrez Prat, Sonia Baulies Caballero, Rafael Fábregas Xaudaró, Carmen Ara Pérez, Maria Garcia Gallardo, Francesc Fargas Fábregas
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引用次数: 0

摘要

与乳房切除术相比,保守治疗被认为是早期乳腺癌的标准治疗方法,在肿瘤安全性方面没有差异。然而,在某些情况下仍然提倡乳房切除术。肿瘤整形手术的概念是为了改善保守手术造成的缺陷而出现的,在保守手术中使用了整形手术技术,并且在减少乳房切除术的适应症方面也有附加价值。在此背景下,本综述的目的是分析局部晚期乳腺癌极端肿瘤整形手术的现有科学证据。材料和方法我们在Medline数据库中使用术语“极端肿瘤成形术”或“极端肿瘤成形术”进行文献检索,共发现17篇出版物。最后,应用纳入和排除标准对6篇文献进行分析。结果极端肿瘤成形术后再切除率为0% ~ 37.8%,转归率为0% ~ 13.5%。轻微并发症的最高发生率为24%,主要并发症的最高发生率为10%,没有延迟开始辅助治疗。满意度评分在75%以上。这些结果与传统的肿瘤整形手术和乳房切除术比较有利。结论对于10年局部复发率小于10%的患者,双侧肿瘤成形术可作为乳房切除术重建的保守选择,并发症发生率低,患者满意度好。然而,需要前瞻性随机试验来提高证据的质量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Oncoplastia extrema, ¿alternativa a la mastectomía? Revisión de la literatura

Introduction

Conservative treatment is considered the standard of care for early stages of breast cancer with no difference in oncological safety compared to mastectomy. However, there are still certain scenarios in which mastectomy is advocated. The concept of oncoplastic surgery has emerged to improve the defects resulting from conservative surgery, in which plastic surgery techniques are used and which could also have added value in reducing the indications for mastectomy. In this context, the aim of this review is to analyse the current scientific evidence on extreme oncoplastic surgery in locally advanced breast cancers.

Materials and methods

We undertook a search of the literature published in the Medline database using the terms "extreme oncoplasty" OR "extreme oncoplastic", and found a total of 17 publications. Finally, 6 articles were analysed, after applying the inclusion and exclusion criteria.

Results

The re-excision rate after extreme oncoplasty ranged from 0%-37.8% with a conversion rate to mastectomy of 0%–13.5%. The highest rate of minor complications was 24% and of major complications was 10%, with no delay in the initiation of adjuvant treatment. Satisfaction scores of more than 75% were obtained. These results compare favourably with conventional oncoplastic surgery and mastectomy.

Conclusions

Extreme oncoplasty may be a conservative alternative to mastectomy with reconstruction in a selected group of patients with local recurrence of less than 10% at 10 years, with a low complication rate and good patient satisfaction. However, prospective randomised trials are needed to improve the quality of the evidence.

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来源期刊
Revista de Senologia y Patologia Mamaria
Revista de Senologia y Patologia Mamaria Medicine-Obstetrics and Gynecology
CiteScore
0.30
自引率
0.00%
发文量
74
审稿时长
63 days
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