[PSA及其衍生生物标志物(总PSA、游离PSA、p2PSA)的免疫分析特征]。

IF 0.4 4区医学 Q4 MEDICAL LABORATORY TECHNOLOGY

Annales de biologie clinique Pub Date : 2023-03-15 DOI:10.1684/abc.2023.1782

Cédric Desbène, Mathieu Boissan, Sylvain Loric, Pierre-Jean Lamy, Laurence Piéroni

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引用次数: 0

摘要

前列腺特异性抗原(PSA)是推荐用于前列腺癌个体筛查和随访的肿瘤标志物。本文综述了前列腺特异性抗原亚型的主要结构和生理资料:总PSA、游离PSA、[-2]prosa(也称为p2PSA)。它描述了这些不同参数的分析前、分析中和分析后的条件。它介绍了对前列腺癌(初始诊断和随访)管理的结果和推导出的计算指数(游离/总PSA比率，前列腺健康指数或PHI)的解释。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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[Immuno-analytical characteristics of PSA and derived biomarkers (total PSA, free PSA, p2PSA)].

Prostate-specific antigen (PSA) is the recommended tumor marker for individual screening and follow-up of prostate cancer. This paper reviews main structural and physiological data about prostate specific antigen isoforms: total PSA, free PSA, [-2]proPSA (also named p2PSA). It describes the pre-, per- and post-analytical conditions for these different parameters. It presents the interpretation of results and derived calculated indices (free/total PSA ratio, Prostate Health Index or PHI) for the management of prostate cancer (initial diagnosis and follow-up).

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来源期刊

Annales de biologie clinique 医学-医学：研究与实验

CiteScore

0.80

自引率

20.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Multidisciplinary information with direct relevance to everyday practice Annales de Biologie Clinique, the official journal of the French Society of Clinical Biology (SFBC), supports biologists in areas including continuing education, laboratory accreditation and technique validation. With original articles, abstracts and accounts of everyday practice, the journal provides details of advances in knowledge, techniques and equipment, as well as a forum for discussion open to the entire community.