The autopsy for sudden unexpected death in infancy

The investigation of a case of sudden unexpected death in infancy (SUDI) is a multidisciplinary process requiring a death scene investigation, a review of the relevant clinical history and a detailed autopsy examination. Autopsy examinations should be performed by pathologists with experience in paediatric pathology and follow a detailed protocol with specific ancillary investigations including skeletal radiology, a full histological examination of all major organs and microbiological, biochemical and metabolic studies. On completion of all the investigations, the final autopsy findings should be discussed at a multidisciplinary case review involving paediatric and primary care input. It is essential that the family of the deceased infant are supported by the local SUDI paediatrician throughout the investigation and that they are kept fully informed of progress and the final conclusion, which should be determined after completion of the case review.