MAFLD的非药物治疗方案:实用指南。

IF 3.9 3区 医学 Q2 ENDOCRINOLOGY & METABOLISM
Therapeutic Advances in Endocrinology and Metabolism Pub Date : 2023-03-21 eCollection Date: 2023-01-01 DOI:10.1177/20420188231160394
José Tadeu Stefano, Sebastião Mauro Bezerra Duarte, Renato Gama Ribeiro Leite Altikes, Claudia P Oliveira
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引用次数: 0

摘要

改变生活方式应该是治疗代谢功能障碍相关性脂肪肝(MAFLD)的主要基础,目的是增加能量消耗、减少能量摄入和改善营养摄入的质量。由于脂肪肝是一种多因素疾病,因此体育锻炼、改善饮食结构和可能的药物干预等方法同时使用会更有效,但同时使用则会损害其应用效果。MAFLD 的主要治疗方法是改变生活方式,包括饮食、活动、锻炼和减肥。训练处方的变量,如体育锻炼的类型(有氧运动或力量训练)、每周的频率以及最适合治疗 MAFLD 的强度仍不确定,也就是说,必须根据临床条件、并发症以及每个受试者的偏好,因人而异地调整建议。本综述探讨了近期治疗 MAFLD 的各种方案,包括饮食、营养素、肠道微生物群和体育锻炼。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Non-pharmacological management options for MAFLD: a practical guide.

Non-pharmacological management options for MAFLD: a practical guide.

Non-pharmacological management options for MAFLD: a practical guide.

Non-pharmacological management options for MAFLD: a practical guide.

Lifestyle changes should be the main basis for any treatment for metabolic dysfunction-associated fatty liver disease (MAFLD), aiming to increase energy expenditure, reduce energy intake and improve the quality of nutrients consumed. As it is a multifactorial disease, approaches such as physical exercise, a better dietary pattern, and possible pharmacological intervention are shown to be more efficient when used simultaneously to the detriment of their applications. The main treatment for MAFLD is a lifestyle change consisting of diet, activity, exercise, and weight loss. The variables for training prescription such as type of physical exercise (aerobic or strength training), the weekly frequency, and the intensity most indicated for the treatment of MAFLD remain uncertain, that is, the recommendations must be adapted to the clinical conditions comorbidities, and preferences of each subject in a way individual. This review addresses recent management options for MAFLD including diet, nutrients, gut microbiota, and physical exercise.

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来源期刊
Therapeutic Advances in Endocrinology and Metabolism
Therapeutic Advances in Endocrinology and Metabolism Medicine-Endocrinology, Diabetes and Metabolism
CiteScore
7.70
自引率
2.60%
发文量
42
审稿时长
8 weeks
期刊介绍: Therapeutic Advances in Endocrinology and Metabolism delivers the highest quality peer-reviewed articles, reviews, and scholarly comment on pioneering efforts and innovative studies across all areas of endocrinology and metabolism.
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