Juan José Chaves , Juan Carlos Bonilla , Viviana Chaves-Cabezas , Andrés Castro , José Fernando Polo , Oscar Mendoza , Jennifer Correa-Rodríguez , Ana Carolina Piedrahita , Ivan Alberto Romero-Fandiño , María Victoria Caro , Andrea Carolina González , Lisseth Katherine Sánchez , Félix Murcia , Gloria Márquez , Alejandra Benavides , María del Pilar Quiroga , Jorge López , Rafael Parra-Medina
{"title":"哥伦比亚SARS-CoV-2疫苗接种患者的尸检研究","authors":"Juan José Chaves , Juan Carlos Bonilla , Viviana Chaves-Cabezas , Andrés Castro , José Fernando Polo , Oscar Mendoza , Jennifer Correa-Rodríguez , Ana Carolina Piedrahita , Ivan Alberto Romero-Fandiño , María Victoria Caro , Andrea Carolina González , Lisseth Katherine Sánchez , Félix Murcia , Gloria Márquez , Alejandra Benavides , María del Pilar Quiroga , Jorge López , Rafael Parra-Medina","doi":"10.1016/j.patol.2022.09.003","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction and objective</h3><p>A new coronavirus produces a disease designated as coronavirus disease 2019 (COVID-19). Vaccination against COVID-19 has resulted in decreased mortality. Postmortems of vaccinated patients play an important part in the forensic analysis of adverse effects after vaccination, which is essential for determining its efficacy and security. The main objective of this study was to describe the results of autopsies of patients vaccinated for SARS-CoV-2 carried out in two major centers in Colombia.</p></div><div><h3>Materials and methods</h3><p>A descriptive cross-sectional study of 121 autopsies was performed following Colombian regulations in two main hospitals in Bogotá, Colombia, between March 1st and April 31st, 2021.</p></div><div><h3>Results</h3><p>118 of the 121 patients (97.52%) had been vaccinated with CoronaVac (Sinovac); only 3 had received other vaccines. Sudden cardiac death was the leading cause of death, with pulmonary embolism another critical finding. No relation between the cause of death and vaccination against SARS-CoV-2 was found.</p></div><div><h3>Conclusions</h3><p>A clinical autopsy is a vital for an accurate post-mortem diagnosis. Any relation between the SARS-CoV-2 vaccine and the cause of death should be carefully studied in order to provide the general public with evidence-based information about the safety of the vaccination.</p></div>","PeriodicalId":39194,"journal":{"name":"Revista Espanola de Patologia","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"A postmortem study of patients vaccinated for SARS-CoV-2 in Colombia\",\"authors\":\"Juan José Chaves , Juan Carlos Bonilla , Viviana Chaves-Cabezas , Andrés Castro , José Fernando Polo , Oscar Mendoza , Jennifer Correa-Rodríguez , Ana Carolina Piedrahita , Ivan Alberto Romero-Fandiño , María Victoria Caro , Andrea Carolina González , Lisseth Katherine Sánchez , Félix Murcia , Gloria Márquez , Alejandra Benavides , María del Pilar Quiroga , Jorge López , Rafael Parra-Medina\",\"doi\":\"10.1016/j.patol.2022.09.003\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction and objective</h3><p>A new coronavirus produces a disease designated as coronavirus disease 2019 (COVID-19). Vaccination against COVID-19 has resulted in decreased mortality. Postmortems of vaccinated patients play an important part in the forensic analysis of adverse effects after vaccination, which is essential for determining its efficacy and security. The main objective of this study was to describe the results of autopsies of patients vaccinated for SARS-CoV-2 carried out in two major centers in Colombia.</p></div><div><h3>Materials and methods</h3><p>A descriptive cross-sectional study of 121 autopsies was performed following Colombian regulations in two main hospitals in Bogotá, Colombia, between March 1st and April 31st, 2021.</p></div><div><h3>Results</h3><p>118 of the 121 patients (97.52%) had been vaccinated with CoronaVac (Sinovac); only 3 had received other vaccines. Sudden cardiac death was the leading cause of death, with pulmonary embolism another critical finding. No relation between the cause of death and vaccination against SARS-CoV-2 was found.</p></div><div><h3>Conclusions</h3><p>A clinical autopsy is a vital for an accurate post-mortem diagnosis. Any relation between the SARS-CoV-2 vaccine and the cause of death should be carefully studied in order to provide the general public with evidence-based information about the safety of the vaccination.</p></div>\",\"PeriodicalId\":39194,\"journal\":{\"name\":\"Revista Espanola de Patologia\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista Espanola de Patologia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1699885522000642\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Espanola de Patologia","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1699885522000642","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
A postmortem study of patients vaccinated for SARS-CoV-2 in Colombia
Introduction and objective
A new coronavirus produces a disease designated as coronavirus disease 2019 (COVID-19). Vaccination against COVID-19 has resulted in decreased mortality. Postmortems of vaccinated patients play an important part in the forensic analysis of adverse effects after vaccination, which is essential for determining its efficacy and security. The main objective of this study was to describe the results of autopsies of patients vaccinated for SARS-CoV-2 carried out in two major centers in Colombia.
Materials and methods
A descriptive cross-sectional study of 121 autopsies was performed following Colombian regulations in two main hospitals in Bogotá, Colombia, between March 1st and April 31st, 2021.
Results
118 of the 121 patients (97.52%) had been vaccinated with CoronaVac (Sinovac); only 3 had received other vaccines. Sudden cardiac death was the leading cause of death, with pulmonary embolism another critical finding. No relation between the cause of death and vaccination against SARS-CoV-2 was found.
Conclusions
A clinical autopsy is a vital for an accurate post-mortem diagnosis. Any relation between the SARS-CoV-2 vaccine and the cause of death should be carefully studied in order to provide the general public with evidence-based information about the safety of the vaccination.
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