{"title":"你的诊断是什么?","authors":"Latika Chawla, Ankita Yadav, Mamta Sah, Shilpa Panta, Nevetha Ravichandran, Ria M, Shalini Rajaram","doi":"10.4274/jtgga.galenos.2022.2022-6-13","DOIUrl":null,"url":null,"abstract":"A 38-year-old lady presented with a painful swelling in the umbilicus, together with a history of increased pain and bleeding from the swelling at the time of menstruation for the last seven months. Her menstrual cycles were regular, with average flow and no dysmenorrhea. She had two living children, both were delivered vaginally. There was no history of pelvic pain, infertility, treatment for infertility, pelvic/abdominal surgery, or caesarean section. Examination revealed a 1.0x0.5 cm firm, tender, reddish-blue colored nodular swelling in the abdominal wall, located just inferior to the umbilical ring with well-defined margins and a regular surface (Figure 1). Pelvic examination was essentially normal with a multiparous-sized uterus that was anteverted, mobile, and non-tender. Both fornices were free and non-tender. The rectovaginal septum was free and there were no nodules in the pouch of Douglas. Ultrasound revealed a well-defined, hetero-echoic lesion with a peripheral rim of colour lying infra-umbilically, superficial to the rectus sheath. The same lesion appeared hyperintense on T1/T2 magnetic resonance imaging (MRI) with post-contrast enhancement. The abdomen and pelvis were found to be normal on MRI. The patient was taken up for surgical excision of the nodule. Radical omphalectomy was performed. A peri-umbilical incision was made. Umbilicus, underlying nodule, and the surrounding area of fibrosis were dissected with a 5 mm clear margin using diathermy (Figure 2). The patient is on follow-up and is free of the disease at 18 months after surgery.","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2023-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e6/51/JTGGA-24-74.PMC10019007.pdf","citationCount":"0","resultStr":"{\"title\":\"What is your diagnosis?\",\"authors\":\"Latika Chawla, Ankita Yadav, Mamta Sah, Shilpa Panta, Nevetha Ravichandran, Ria M, Shalini Rajaram\",\"doi\":\"10.4274/jtgga.galenos.2022.2022-6-13\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A 38-year-old lady presented with a painful swelling in the umbilicus, together with a history of increased pain and bleeding from the swelling at the time of menstruation for the last seven months. Her menstrual cycles were regular, with average flow and no dysmenorrhea. She had two living children, both were delivered vaginally. There was no history of pelvic pain, infertility, treatment for infertility, pelvic/abdominal surgery, or caesarean section. Examination revealed a 1.0x0.5 cm firm, tender, reddish-blue colored nodular swelling in the abdominal wall, located just inferior to the umbilical ring with well-defined margins and a regular surface (Figure 1). Pelvic examination was essentially normal with a multiparous-sized uterus that was anteverted, mobile, and non-tender. Both fornices were free and non-tender. The rectovaginal septum was free and there were no nodules in the pouch of Douglas. Ultrasound revealed a well-defined, hetero-echoic lesion with a peripheral rim of colour lying infra-umbilically, superficial to the rectus sheath. The same lesion appeared hyperintense on T1/T2 magnetic resonance imaging (MRI) with post-contrast enhancement. The abdomen and pelvis were found to be normal on MRI. The patient was taken up for surgical excision of the nodule. Radical omphalectomy was performed. A peri-umbilical incision was made. Umbilicus, underlying nodule, and the surrounding area of fibrosis were dissected with a 5 mm clear margin using diathermy (Figure 2). The patient is on follow-up and is free of the disease at 18 months after surgery.\",\"PeriodicalId\":1,\"journal\":{\"name\":\"Accounts of Chemical Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":16.4000,\"publicationDate\":\"2023-03-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e6/51/JTGGA-24-74.PMC10019007.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Accounts of Chemical Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4274/jtgga.galenos.2022.2022-6-13\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4274/jtgga.galenos.2022.2022-6-13","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
A 38-year-old lady presented with a painful swelling in the umbilicus, together with a history of increased pain and bleeding from the swelling at the time of menstruation for the last seven months. Her menstrual cycles were regular, with average flow and no dysmenorrhea. She had two living children, both were delivered vaginally. There was no history of pelvic pain, infertility, treatment for infertility, pelvic/abdominal surgery, or caesarean section. Examination revealed a 1.0x0.5 cm firm, tender, reddish-blue colored nodular swelling in the abdominal wall, located just inferior to the umbilical ring with well-defined margins and a regular surface (Figure 1). Pelvic examination was essentially normal with a multiparous-sized uterus that was anteverted, mobile, and non-tender. Both fornices were free and non-tender. The rectovaginal septum was free and there were no nodules in the pouch of Douglas. Ultrasound revealed a well-defined, hetero-echoic lesion with a peripheral rim of colour lying infra-umbilically, superficial to the rectus sheath. The same lesion appeared hyperintense on T1/T2 magnetic resonance imaging (MRI) with post-contrast enhancement. The abdomen and pelvis were found to be normal on MRI. The patient was taken up for surgical excision of the nodule. Radical omphalectomy was performed. A peri-umbilical incision was made. Umbilicus, underlying nodule, and the surrounding area of fibrosis were dissected with a 5 mm clear margin using diathermy (Figure 2). The patient is on follow-up and is free of the disease at 18 months after surgery.
期刊介绍:
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.