Saranya Shankar , Sugashini Settu , Gayathri Segaran , Ranjitha Dhevi V. Sundar , Lokesh Ravi
{"title":"龙血树叶的植物化学成分及其抗菌、抗氧化和抗炎意义","authors":"Saranya Shankar , Sugashini Settu , Gayathri Segaran , Ranjitha Dhevi V. Sundar , Lokesh Ravi","doi":"10.1016/j.biori.2018.09.002","DOIUrl":null,"url":null,"abstract":"<div><p>The present study aims to analyze the antimicrobial, antioxidant and anti-inflammatory activity of <em>Dracaena mahatma</em> leaf extract. Qualitative phytochemical screening of leaf powder confirmed the presence of tannins, alkaloids, phenols, terpenoids, sterols, triterpenes and anthraquinone glycosides. GC-MS analysis of methanolic extract suggested the presence of 2 unknown compounds and 8 known phytochemicals, of which benzene-(1,6-hexanediylidene)tetrakis constituted a maximum percentage of the crude extract. The total phenolic content of the crude extract was found to be 32.9<!--> <!-->±<!--> <!-->0.002<!--> <!-->GAE/g. Crude extract demonstrated 90% antioxidant activity in DPPH assay at 100<!--> <!-->μg/ml concentration and also demonstrated significant antioxidant activity in FRAP assay at 100<!--> <!-->μg/ml concentration. The crude extract did not show any antagonism against fungal pathogens <em>Aspergillus niger</em> and <em>Aspergillus flavus</em>. Crude extract demonstrated significant antibacterial activity against 5 studied pathogen, with the highest antagonism against <em>Escherichia coli</em> with a zone of inhibition of 22<!--> <!-->mm at 10<!--> <!-->mg/well concentration.</p></div>","PeriodicalId":100187,"journal":{"name":"Biotechnology Research and Innovation","volume":"2 1","pages":"Pages 1-8"},"PeriodicalIF":0.0000,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.biori.2018.09.002","citationCount":"8","resultStr":"{\"title\":\"Phytochemical constituents of Dracaena mahatma leaves and their anti-bacterial, anti-oxidant and anti-inflammatory significance\",\"authors\":\"Saranya Shankar , Sugashini Settu , Gayathri Segaran , Ranjitha Dhevi V. Sundar , Lokesh Ravi\",\"doi\":\"10.1016/j.biori.2018.09.002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>The present study aims to analyze the antimicrobial, antioxidant and anti-inflammatory activity of <em>Dracaena mahatma</em> leaf extract. Qualitative phytochemical screening of leaf powder confirmed the presence of tannins, alkaloids, phenols, terpenoids, sterols, triterpenes and anthraquinone glycosides. GC-MS analysis of methanolic extract suggested the presence of 2 unknown compounds and 8 known phytochemicals, of which benzene-(1,6-hexanediylidene)tetrakis constituted a maximum percentage of the crude extract. The total phenolic content of the crude extract was found to be 32.9<!--> <!-->±<!--> <!-->0.002<!--> <!-->GAE/g. Crude extract demonstrated 90% antioxidant activity in DPPH assay at 100<!--> <!-->μg/ml concentration and also demonstrated significant antioxidant activity in FRAP assay at 100<!--> <!-->μg/ml concentration. The crude extract did not show any antagonism against fungal pathogens <em>Aspergillus niger</em> and <em>Aspergillus flavus</em>. Crude extract demonstrated significant antibacterial activity against 5 studied pathogen, with the highest antagonism against <em>Escherichia coli</em> with a zone of inhibition of 22<!--> <!-->mm at 10<!--> <!-->mg/well concentration.</p></div>\",\"PeriodicalId\":100187,\"journal\":{\"name\":\"Biotechnology Research and Innovation\",\"volume\":\"2 1\",\"pages\":\"Pages 1-8\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.biori.2018.09.002\",\"citationCount\":\"8\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biotechnology Research and Innovation\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2452072118300248\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biotechnology Research and Innovation","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2452072118300248","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Phytochemical constituents of Dracaena mahatma leaves and their anti-bacterial, anti-oxidant and anti-inflammatory significance
The present study aims to analyze the antimicrobial, antioxidant and anti-inflammatory activity of Dracaena mahatma leaf extract. Qualitative phytochemical screening of leaf powder confirmed the presence of tannins, alkaloids, phenols, terpenoids, sterols, triterpenes and anthraquinone glycosides. GC-MS analysis of methanolic extract suggested the presence of 2 unknown compounds and 8 known phytochemicals, of which benzene-(1,6-hexanediylidene)tetrakis constituted a maximum percentage of the crude extract. The total phenolic content of the crude extract was found to be 32.9 ± 0.002 GAE/g. Crude extract demonstrated 90% antioxidant activity in DPPH assay at 100 μg/ml concentration and also demonstrated significant antioxidant activity in FRAP assay at 100 μg/ml concentration. The crude extract did not show any antagonism against fungal pathogens Aspergillus niger and Aspergillus flavus. Crude extract demonstrated significant antibacterial activity against 5 studied pathogen, with the highest antagonism against Escherichia coli with a zone of inhibition of 22 mm at 10 mg/well concentration.
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