脑岛的作用:精神分裂症患者脑肿瘤的诊断

Q4 Medicine

Psiquiatria Biologica Pub Date : 2021-09-01 DOI:10.1016/j.psiq.2021.100333

Patricia Latorre-Forcén , Isabel Laporta-Herrero , Soraya Rebollar González

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引用次数: 0

摘要

神经胶质瘤是一种罕见的生长缓慢的脑肿瘤。脑岛与自我认知、心理理论、人际关系、现实扭曲和阳性症状的出现有关。目前关于这类肿瘤在脑岛和精神病方面的文献很少。临床病例男性，32岁，诊断为偏执型精神分裂症伴明显幻听，常规脑MRI示左岛区低度胶质瘤。我们根据这一发现讨论精神症状的持久性和难治性之间可能的关系。脑岛可能是精神分裂症患者受影响的主要脑区。在精神病患者中，岛岛结构的缺陷与阳性和阴性症状的存在和严重程度有关。他们的双侧脑岛灰质体积减少，尤其是右侧。

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The role of the insula: Diagnosis of a brain tumor in a patient with schizophrenia

Introduction

Gliomas are rare, slow-growing brain tumors. The insula is related to self-knowledge, theory of the mind, interpersonal relationships, distortion of reality and the appearance of positive symptoms. There is little current literature on these type of tumors in the insula and psychosis.

Clinical case

A 32-year-old male patient, diagnosed with Paranoid Schizophrenia with significant auditory hallucinations, and a low-grade glioma in the left insular region on routine brain MRI examination. We discuss the possible relationship between the persistence and refractoriness of psychotic symptoms with this finding.

Discussion

The insula may be the main affected brain region in schizophrenia. In psychotic patients, deficits in the insular structure are associated with the presence and severity of positive and negative symptoms. They had reduced volumes of bilateral gray matter from the insula, especially on the right side.

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来源期刊

Psiquiatria Biologica Medicine-Psychiatry and Mental Health

CiteScore

0.40

自引率

0.00%

发文量

期刊介绍： Es la Publicación Oficial de la Sociedad Española de Psiquiatría Biológica. Los recientes avances en el conocimiento de la bioquímica y de la fisiología cerebrales y el progreso en general en el campo de las neurociencias han abierto el camino al desarrollo de la psiquiatría biológica, fundada sobre bases anatomofisiológicas, más sólidas y científicas que la psiquiatría tradicional.