使用VAP脂质面板检测、评估和治疗冠心病“危险”患者

Kenneth French , Yi Wang , Jianghua Jia , Yusheng Zhang
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引用次数: 0

摘要

在过去的几十年里,多项临床试验已经证明了低密度脂蛋白胆固醇(LDL-C)以外的血脂异常在预测动脉粥样硬化和心血管疾病风险方面的作用。近年来,脂蛋白标记物与LDL-C一起使用时,帮助医疗保健提供者根据心血管风险谱评估患者的风险。在这篇综述中,我们将讨论传统的脂蛋白检测在高危人群中失败的一些重要原因,以及垂直自动谱(VAP)脂质面板的独特脂蛋白检测如何为其管理和治疗提供重要的清晰度。我们还将讨论一些新的试验,这些试验解决了新的风险标记,即使在调整了传统的心血管疾病风险因素后,也有可靠的结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Using the VAP lipid panel for the detection, evaluation, and treatment of patients “at risk” for CAD

In the past several decades, multiple clinical trials have demonstrated the effects of dyslipidemia beyond low density lipoprotein cholesterol (LDL-C) on predicting risk for atherosclerosis and cardiovascular disease. In recent years there has been a proliferation of lipoprotein markers that, when used with LDL-C, help healthcare providers assess risk of patients on the basis of the cardiovascular risk spectrum. In this review, we will discuss some of the important reasons why traditional lipoprotein testing has failed in high risk populations and how unique lipoprotein testing by the Vertical Auto Profile (VAP) Lipid panel is to provide significant clarity to a difficult disease for its management and treatment. We will also discuss some of the new trials that address newer markers of risk that have robust outcomes even after adjusting for traditional cardiovascular disease risk factors.

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