{"title":"发展中国家成年女性月经初潮年龄及其与血压的关系:一项系统回顾和荟萃分析。","authors":"Gaili Wang, Weihao Shao, Xiaorui Chen, Caifang Zheng, Bowen Zhang, Weidong Zhang","doi":"10.1080/03014460.2023.2184866","DOIUrl":null,"url":null,"abstract":"<p><strong>Context: </strong>Evidence about the effect of age at menarche (AAM) on blood pressure (BP) has largely been drawn from studies in developed countries. Studies in developing countries are expanding recently but have not been summarised.</p><p><strong>Objective: </strong>To systematically explore the association between AAM and BP and the potential modifiers in developing countries.</p><p><strong>Methods: </strong>We searched PubMed, Embase, and Web of Science for publications until March 2022. A random-effects model was used to calculate the pooled relative risk (RR) with 95% confidence interval (CI).</p><p><strong>Results: </strong>Twenty studies were eligible. In studies with participants' mean age at BP assessment <55 years, women in the oldest group as compared with the middle or the youngest group of AAM had a higher risk of hypertension in those studies without adjustment for confounders (RR 1.79, 95% CI 1.41-2.28, <i>I<sup>2</sup></i>=97.0%), those with adjustment for confounders excluding adiposity (1.25,1.04-1.51, <i>I<sup>2</sup></i>=84.8%), and those with adjustment for confounders including adiposity (1.38,1.03-1.86, <i>I<sup>2</sup></i>=91.8%). In studies with participants' mean age at BP assessment ≥55 years, no significant differences were found for studies without adjustment for confounders (RR 1.07, 95% CI 0.78-1.47, <i>I<sup>2</sup>=</i>90.3%), studies with adjustment for confounders excluding adiposity (0.85, 0.78-0.92, <i>I<sup>2</sup></i>=12.3%), or studies with adjustment for confounders including adiposity (0.95, 0.80-1.11, <i>I<sup>2</sup></i>=45.5%). A similar association was observed between AAM and baseline systolic BP and diabolic BP.</p><p><strong>Conclusion: </strong>Late menarche was associated with a higher risk of BP and this association was modified by age and adiposity in developing countries.</p>","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Age at menarche and its association with blood pressure in adult women of developing countries: a systematic review and meta-analysis.\",\"authors\":\"Gaili Wang, Weihao Shao, Xiaorui Chen, Caifang Zheng, Bowen Zhang, Weidong Zhang\",\"doi\":\"10.1080/03014460.2023.2184866\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Context: </strong>Evidence about the effect of age at menarche (AAM) on blood pressure (BP) has largely been drawn from studies in developed countries. Studies in developing countries are expanding recently but have not been summarised.</p><p><strong>Objective: </strong>To systematically explore the association between AAM and BP and the potential modifiers in developing countries.</p><p><strong>Methods: </strong>We searched PubMed, Embase, and Web of Science for publications until March 2022. A random-effects model was used to calculate the pooled relative risk (RR) with 95% confidence interval (CI).</p><p><strong>Results: </strong>Twenty studies were eligible. In studies with participants' mean age at BP assessment <55 years, women in the oldest group as compared with the middle or the youngest group of AAM had a higher risk of hypertension in those studies without adjustment for confounders (RR 1.79, 95% CI 1.41-2.28, <i>I<sup>2</sup></i>=97.0%), those with adjustment for confounders excluding adiposity (1.25,1.04-1.51, <i>I<sup>2</sup></i>=84.8%), and those with adjustment for confounders including adiposity (1.38,1.03-1.86, <i>I<sup>2</sup></i>=91.8%). In studies with participants' mean age at BP assessment ≥55 years, no significant differences were found for studies without adjustment for confounders (RR 1.07, 95% CI 0.78-1.47, <i>I<sup>2</sup>=</i>90.3%), studies with adjustment for confounders excluding adiposity (0.85, 0.78-0.92, <i>I<sup>2</sup></i>=12.3%), or studies with adjustment for confounders including adiposity (0.95, 0.80-1.11, <i>I<sup>2</sup></i>=45.5%). A similar association was observed between AAM and baseline systolic BP and diabolic BP.</p><p><strong>Conclusion: </strong>Late menarche was associated with a higher risk of BP and this association was modified by age and adiposity in developing countries.</p>\",\"PeriodicalId\":1,\"journal\":{\"name\":\"Accounts of Chemical Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":16.4000,\"publicationDate\":\"2023-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Accounts of Chemical Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1080/03014460.2023.2184866\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/03014460.2023.2184866","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
摘要
背景:月经初潮年龄(AAM)对血压(BP)影响的证据主要来自发达国家的研究。发展中国家的研究最近正在扩大，但尚未得到总结。目的:系统探讨发展中国家AAM和BP之间的关系及潜在的修饰剂。方法:我们检索PubMed, Embase和Web of Science直到2022年3月的出版物。采用随机效应模型计算合并相对危险度(RR)，置信区间为95%。结果:20项研究符合条件。在受试者在血压评估时的平均年龄(I2=97.0%)、不包括肥胖的混杂因素调整的研究(1.25,1.04-1.51,I2=84.8%)和包括肥胖的混杂因素调整的研究(1.38,1.03-1.86,I2=91.8%)。在受试者血压评估时平均年龄≥55岁的研究中，未校正混杂因素的研究(RR 1.07, 95% CI 0.78-1.47, I2=90.3%)、校正不包括肥胖的混杂因素的研究(0.85,0.78-0.92,I2=12.3%)或校正包括肥胖的混杂因素的研究(0.95,0.80-1.11,I2=45.5%)均未发现显著差异。在AAM与基线收缩压和恶魔压之间观察到类似的关联。结论:在发展中国家，月经初潮晚与BP的高风险相关，这种关联被年龄和肥胖所改变。
Age at menarche and its association with blood pressure in adult women of developing countries: a systematic review and meta-analysis.
Context: Evidence about the effect of age at menarche (AAM) on blood pressure (BP) has largely been drawn from studies in developed countries. Studies in developing countries are expanding recently but have not been summarised.
Objective: To systematically explore the association between AAM and BP and the potential modifiers in developing countries.
Methods: We searched PubMed, Embase, and Web of Science for publications until March 2022. A random-effects model was used to calculate the pooled relative risk (RR) with 95% confidence interval (CI).
Results: Twenty studies were eligible. In studies with participants' mean age at BP assessment <55 years, women in the oldest group as compared with the middle or the youngest group of AAM had a higher risk of hypertension in those studies without adjustment for confounders (RR 1.79, 95% CI 1.41-2.28, I2=97.0%), those with adjustment for confounders excluding adiposity (1.25,1.04-1.51, I2=84.8%), and those with adjustment for confounders including adiposity (1.38,1.03-1.86, I2=91.8%). In studies with participants' mean age at BP assessment ≥55 years, no significant differences were found for studies without adjustment for confounders (RR 1.07, 95% CI 0.78-1.47, I2=90.3%), studies with adjustment for confounders excluding adiposity (0.85, 0.78-0.92, I2=12.3%), or studies with adjustment for confounders including adiposity (0.95, 0.80-1.11, I2=45.5%). A similar association was observed between AAM and baseline systolic BP and diabolic BP.
Conclusion: Late menarche was associated with a higher risk of BP and this association was modified by age and adiposity in developing countries.
期刊介绍：
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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