预防念珠菌在医疗机构传播的策略。

IF 2.3 Q3 INFECTIOUS DISEASES
Current Fungal Infection Reports Pub Date : 2023-01-01 Epub Date: 2023-01-26 DOI:10.1007/s12281-023-00451-7
Suhail Ahmad, Mohammad Asadzadeh
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引用次数: 0

摘要

综述的目的:白色念珠菌(Candida auris)是一种新近被确认的酵母病原体,由于其准确鉴定、对抗真菌药物的内在和后天耐药性以及容易污染环境导致医疗机构爆发克隆疫情等相关问题,已成为一种主要的公共卫生威胁。这些疾病的爆发与高死亡率有关,尤其是在重症监护环境下患有多种并发症的老年患者中。本综述的目的是重点介绍在医疗机构中预防法氏囊病传播的策略:最近的研究结果:定植的患者会将法氏囊菌脱落到周围环境中,从而污染周围的设备。即使通过严格的净化程序也无法消除这种病菌,而且在密切接触过程中很容易传染给新病人,导致疾病爆发。目前正在努力快速识别感染法氏囊菌/法氏囊菌定植患者,确定其对抗真菌药物的敏感性,并对环境进行有效的清洁和净化,隔离定植患者,以防止进一步传播:摘要:快速准确地识别感染/结肠球菌的住院患者,快速检测其药敏模式,并适当使用感染控制措施,有助于遏制这种高致病性酵母菌在医疗机构中的传播,预防/控制疫情爆发。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Strategies to Prevent Transmission of Candida auris in Healthcare Settings.

Purpose of review: Candida auris, a recently recognized yeast pathogen, has become a major public health threat due to the problems associated with its accurate identification, intrinsic and acquired resistance to antifungal drugs, and its potential to easily contaminate the environment causing clonal outbreaks in healthcare facilities. These outbreaks are associated with high mortality rates particularly among older patients with multiple comorbidities under intensive care settings. The purpose of this review is to highlight strategies that are being adapted to prevent transmission of C. auris in healthcare settings.

Recent findings: Colonized patients shed C. auris into their environment which contaminates surrounding equipment. It resists elimination even by robust decontamination procedures and is easily transmitted to new patients during close contact resulting in outbreaks. Efforts are being made to rapidly identify C. auris-infected/C. auris-colonized patients, to determine its susceptibility to antifungals, and to perform effective cleaning and decontamination of the environment and isolation of colonized patients to prevent further transmission.

Summary: Rapid and accurate identification of hospitalized patients infected/colonized with C. auris, rapid detection of its susceptibility patterns, and appropriate use of infection control measures can help to contain the spread of this highly pathogenic yeast in healthcare settings and prevent/control outbreaks.

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来源期刊
Current Fungal Infection Reports
Current Fungal Infection Reports INFECTIOUS DISEASES-
CiteScore
3.10
自引率
7.10%
发文量
20
期刊介绍: This journal intends to provide clear, insightful, balanced contributions that review the most important, recently published clinical findings related to the diagnosis, treatment, management, and prevention of fungal infections. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as advances in diagnosis, current and emerging management approaches, and genomics and pathogenesis. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. Commentaries from well-known figures in the field are also provided, and an international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research.
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