{"title":"雌激素参与结直肠癌发病机制的现状。","authors":"R. Anghel, G. Serbanescu","doi":"10.4183/aeb.2021.400","DOIUrl":null,"url":null,"abstract":"Gastrointestinal effects of estrogens are emerging as an important topic in colorectal cancer management. Current research demonstrated the link between inflammation and this malignancy, so important estrogen dependent mediators of the inflammatory response have been identified. Radioresistance and chemoresistance still represent an important cause of therapeutic failure in colorectal cancer and lead to further studies of colorectal carcinogenesis and predictive markers.","PeriodicalId":6910,"journal":{"name":"Acta endocrinologica","volume":"16 8","pages":"422-425"},"PeriodicalIF":0.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Actualities in Involvement of Estrogens in the Pathogenesis of Colorectal Cancer.\",\"authors\":\"R. Anghel, G. Serbanescu\",\"doi\":\"10.4183/aeb.2021.400\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Gastrointestinal effects of estrogens are emerging as an important topic in colorectal cancer management. Current research demonstrated the link between inflammation and this malignancy, so important estrogen dependent mediators of the inflammatory response have been identified. Radioresistance and chemoresistance still represent an important cause of therapeutic failure in colorectal cancer and lead to further studies of colorectal carcinogenesis and predictive markers.\",\"PeriodicalId\":6910,\"journal\":{\"name\":\"Acta endocrinologica\",\"volume\":\"16 8\",\"pages\":\"422-425\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta endocrinologica\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4183/aeb.2021.400\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta endocrinologica","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4183/aeb.2021.400","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Actualities in Involvement of Estrogens in the Pathogenesis of Colorectal Cancer.
Gastrointestinal effects of estrogens are emerging as an important topic in colorectal cancer management. Current research demonstrated the link between inflammation and this malignancy, so important estrogen dependent mediators of the inflammatory response have been identified. Radioresistance and chemoresistance still represent an important cause of therapeutic failure in colorectal cancer and lead to further studies of colorectal carcinogenesis and predictive markers.
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