声动力和光动力治疗晚期胰腺癌1例报告

Lucy Q. Li
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引用次数: 0

摘要

光动力疗法(PDT)是一种针对某些肿瘤的治疗方法,于1998年获得FDA批准。最近的研究数据表明,一种相关的程序,声动力疗法(SDT),是另一种新的有希望的癌症治疗补充方法。在这里,我们报告了一位晚期胰腺癌患者的临床结果,该患者采用声动力和光动力疗法(SPDT)结合常规疗法进行治疗。患者被当地肿瘤小组病理诊断为转移性胰腺癌(不受尊敬的晚期胰腺癌)。晚期胰腺癌对常规治疗反应不满意。SPDT治疗包括使用一种新的增敏剂Sonoflora a TM (SFa),舌下给药;12小时后,采用光超联合治疗,低剂量化疗同时进行全身治疗(SPDT周期性跟随化疗周期)。患者部分反应良好。结果表明,SPDT可能是治疗胰腺癌的一种新的补充治疗组合。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Sonodynamic and Photodynamic Therapy in Advanced Pancreas Carcinoma - A Case Report
Photodynamic Therapy (PDT) is a therapeutic treatment for certain kinds of tumors, approved by the FDA in 1998. Recent research data shows that a related procedure, Sonodynamic Therapy (SDT), is another new promising complementary method for cancer treatment. Here we report clinical results in an advanced pancreas cancer patient who was treated using a combination of Sonodynamic and Photodynamic Therapy (SPDT), along with conventional therapies. The patient was pathologically diagnosed with metastatic pancreas carcinoma (non-respectable advanced pancreas cancer) by the patient’s local oncology team. The advanced pancreas carcinoma had responded unsatisfactorily to conventional therapies. SPDT treatment involved using a new sensitizing agent Sonoflora a TM (SFa), which was administered sublingually; 12-hour latter, the patient was treated with a combination of light and ultrasound devices, and a low dosage of chemotherapy simultaneously as a whole body treatment (SPDT follows the chemotherapy cycle periodically). Patient had good partial responses. The results indicate that SPDT could be a promising new complementary therapeutic combination for the treatment of pancreas cancer.
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