一种天然口服营养补充剂的成分及其在治疗骨关节炎中的作用

IF 1.9 Q2 ORTHOPEDICS
K. Bharat, N. Manhas, James Gutcho, Joshua Lin, S. Bhattacharyya, Robertus Kounang
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引用次数: 1

摘要

骨关节炎是一种流行的退行性疾病,影响了世界上很大一部分老龄化人口。目前,非甾体类抗炎药和对乙酰氨基酚是治疗骨关节炎患者疼痛的一线药物。然而,一些研究指出,虽然这些药物可以控制疼痛,但它们并不能阻止进行性变性,而且长期使用往往会产生不利的副作用。最近,由于其更有利的副作用,用于控制骨关节炎症状和缓解疾病进展的草药替代品正在得到越来越多的研究。Synogesic是一种新开发的草药补充剂,由著名的骨科医生和理疗师混合,由姜黄、芦丁、生姜根、维生素C、维生素D和乳香草提取物组成。Sharkey等人的一项研究评论了该混合物对膝关节骨关节炎患者的疗效。到目前为止,还没有对这种混合物的成分进行审查。通过研究PubMed和ScienceDirect等知名文献数据库,我们的目标是撰写一篇叙述性综述,探讨这种混合物的各个成分,并深入研究它们的特征,以及它们对骨关节炎患者的作用机制和疗效的最新文献。通过此,我们希望告知临床医生和患者有关补充剂的最新相关研究,并提供关于该补充剂缓解骨关节炎患者病程的潜力的见解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Ingredients of a Natural Oral Nutritional Supplement and Their Role in the Treatment of Osteoarthritis
Osteoarthritis is a prevalent degenerative disease affecting a large portion of the world’s aging population. Currently, nonsteroidal anti-inflammatory drugs and acetaminophen are first-line medications for treating osteoarthritis patients’ pain. However, several studies have noted that while these medications control pain they do not halt progressive degeneration and tend to have an unfavorable side-effect profile with prolonged use. Recently, due to their more favorable side-effect profiles, herbal alternatives for controlling osteoarthritis symptoms and for alleviating the progression of the disease are being increasingly studied. Synogesic is a newly developed herbal supplement blend by renowned orthopedic surgeons and physiatrists consisting of turmeric, rutin, ginger root, vitamin C, vitamin D, and boswellia extracts. A study by Sharkey et al. has commented on the efficacy of the blend on the patients with knee osteoarthritis. So far, a review on the ingredients of the blend has not yet carried outbeen. By exploring prominent literature databases including PubMed and ScienceDirect, our aim is to write a narrative review to explore the individual ingredients of this blend and delve into their characteristics, as well as the most recent literature on their mechanism and efficacy in patients with osteoarthritis. Through this, we hope to inform clinicians and patients alike on relevant up-to-date research on the supplement and provide insight on the potential for this supplement for alleviating the disease course of patients with osteoarthritis.
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来源期刊
CiteScore
4.40
自引率
0.00%
发文量
14
审稿时长
8 weeks
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