口腔溶解膜的研究进展

Pawan S. Avhad, Saurabh D. Nikam, Amit A. Chaudhari, S. Wagh, Meghana S. Rayjade, Prajwal Y. Gosavi
{"title":"口腔溶解膜的研究进展","authors":"Pawan S. Avhad, Saurabh D. Nikam, Amit A. Chaudhari, S. Wagh, Meghana S. Rayjade, Prajwal Y. Gosavi","doi":"10.18231/j.ijpca.2022.030","DOIUrl":null,"url":null,"abstract":"The fast dissolving orally disintegrating film are the designed to dissolve upon contact with wet surface or fluids like saliva, within a few seconds. Like a tablet, capsule, oral liquids there is no need of additional liquids like water. This is the most convenient dosage form for patients and also provides marketing advantages. In pediatric, geriatric and patient who have fear of choking orally disintegrating film is most convenient and popular dosage form. As the drug I directly absorb in blood through mucus membrane in mouth the degradation of drug in GIT and the first pass metabolism of drug is avoided which increase the arability of drug in plasma which increases therapeutic effect.This review gives information about all aspects from today’s point of view and gives idea about evaluation, formulation, manufacturing process of fast dissolving orally disintegrating film.","PeriodicalId":13889,"journal":{"name":"International Journal of Pharmaceutical Chemistry and Analysis","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Review on: Recent advances in mouth dissolving film\",\"authors\":\"Pawan S. Avhad, Saurabh D. Nikam, Amit A. Chaudhari, S. Wagh, Meghana S. Rayjade, Prajwal Y. Gosavi\",\"doi\":\"10.18231/j.ijpca.2022.030\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The fast dissolving orally disintegrating film are the designed to dissolve upon contact with wet surface or fluids like saliva, within a few seconds. Like a tablet, capsule, oral liquids there is no need of additional liquids like water. This is the most convenient dosage form for patients and also provides marketing advantages. In pediatric, geriatric and patient who have fear of choking orally disintegrating film is most convenient and popular dosage form. As the drug I directly absorb in blood through mucus membrane in mouth the degradation of drug in GIT and the first pass metabolism of drug is avoided which increase the arability of drug in plasma which increases therapeutic effect.This review gives information about all aspects from today’s point of view and gives idea about evaluation, formulation, manufacturing process of fast dissolving orally disintegrating film.\",\"PeriodicalId\":13889,\"journal\":{\"name\":\"International Journal of Pharmaceutical Chemistry and Analysis\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-02-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Pharmaceutical Chemistry and Analysis\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.18231/j.ijpca.2022.030\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Pharmaceutical Chemistry and Analysis","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18231/j.ijpca.2022.030","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

这种快速溶解的口腔崩解膜被设计成在接触潮湿的表面或唾液等液体时在几秒钟内溶解。像片剂、胶囊、口服液一样,不需要额外的液体,比如水。这对患者来说是最方便的剂型,也提供了营销优势。口腔崩解片是儿童、老年人和有窒息恐惧的患者最方便、最流行的剂型。由于药物通过口腔粘膜直接吸收到血液中,避免了药物在胃肠道中的降解和药物的第一次代谢,增加了药物在血浆中的可用性,提高了治疗效果。本文从目前的角度对各方面进行了综述,并对快速溶解口腔崩解膜的评价、配方、制造工艺等方面提出了看法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Review on: Recent advances in mouth dissolving film
The fast dissolving orally disintegrating film are the designed to dissolve upon contact with wet surface or fluids like saliva, within a few seconds. Like a tablet, capsule, oral liquids there is no need of additional liquids like water. This is the most convenient dosage form for patients and also provides marketing advantages. In pediatric, geriatric and patient who have fear of choking orally disintegrating film is most convenient and popular dosage form. As the drug I directly absorb in blood through mucus membrane in mouth the degradation of drug in GIT and the first pass metabolism of drug is avoided which increase the arability of drug in plasma which increases therapeutic effect.This review gives information about all aspects from today’s point of view and gives idea about evaluation, formulation, manufacturing process of fast dissolving orally disintegrating film.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信