果阿邦某三级保健中心急性心肌梗死年轻患者(≤45岁)的流行病学概况

Shubham Kumar, Bhargav Dessai
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引用次数: 0

摘要

导读:在印度的年轻人群中,心肌梗死(MI)的发病率正在上升。生活方式的改变是患病率上升的主要原因。尽管年轻心肌梗死的严重程度低于老年患者,但它对个体的发病率很高。青年心肌梗死有可能成为我国的一个重大公共卫生问题,其并发症可导致重大发病率和死亡率。因此,有必要了解危险因素的流行情况,以改进我们预防和管理年轻心肌梗死的策略。目的:研究果阿邦三级保健中心患有急性心肌梗死的年轻患者(≤45岁)的概况。材料与方法:对2019年1月1日至2021年12月31日在Bambolim果阿医学院收治的年龄≤45岁st段抬高型心肌梗死患者进行回顾性记录研究。从这些记录中提取了人体测量数据、人口统计学特征、临床概况、住院时间、并发症和其他细节。结果:176例患者中,饮酒73例(42%),吸烟116例(66%),诊断为高血压48例(28%),诊断为血脂异常92例(48%),诊断为糖尿病34例(20%)。患者中有冠状动脉病史36例(21%),有HTN病史56例(32%)。家族有糖尿病史的53人(30%);其中27人患有糖尿病,10人处于糖尿病前期。56名(31%)参与者在心肌梗死后住院超过7天。48名(27%)患者在心肌梗死后出现并发症。趋势分析显示2型糖尿病(T2DM)、HTN、吸烟和血脂异常与并发症和住院时间增加有显著相关性(P < 0.05)。大多数患者(91%的T2DM, 90%的高血压,83%的血脂异常患者)是在心肌梗死入院后诊断的。结论:我们已经知道,缺血性心脏病(IHD)在一般人群中的发病率已经在上升,在年轻人中也有令人担忧的上升趋势。本研究提供了各种危险因素在年轻心肌梗死中的流行情况。我们研究的并发症随危险因素的增加而上升的趋势使得早期诊断对于更好地管理和预防并发症至关重要。年轻人IHD负担的增加将导致生活质量下降,发病率和死亡率增加,也会增加社会的经济负担。这强调了初级卫生保健系统早期发现糖尿病、HTN和血脂异常的能力建设的重要性,并使人们意识到吸烟和饮酒的不必要影响。如本研究所述,妥善管理和预防上述危险因素将对预防青少年心肌梗死大有帮助。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Epidemiological profile among young patients (≤45 years) suffering from acute myocardial infarction in a tertiary care center in Goa
INTRODUCTION: The incidence of myocardial infarction (MI) is increasing among the young population in India. Change in lifestyle is the main reason for such an increase in prevalence. Although MI in young is less severe than in old patients, it causes a significant morbidity to the individual. Young MI has the potential of being a major public health problem in our country and its complications can cause major morbidity and mortality. Hence, it is necessary to understand the prevalence of risk factors in order to improve our strategies for the prevention and management of young MI. AIM: To study profile of young patients (≤45 years) suffering from acute myocardial infarction in a tertiary care centre in Goa. MATERIALS AND METHODS: A retrospective record-based study was conducted on patients aged ≤45 years who suffered from ST-elevation MI and were admitted in Goa Medical College, Bambolim, from January 1, 2019, to December 31, 2021. Data on anthropometric measurements, demographic characteristics, clinical profile, hospital stay, complications, and other details were extracted from these records. RESULTS: Among the 176 patients, 73 (42%) patients consumed alcohol, 116 (66%) were current smokers, 48 (28%) were diagnosed with hypertension (HTN), 92 (48%) were diagnosed with dyslipidemia, and 34 (20%) were diagnosed with diabetes. Among the patients, 36 (21%) had a history of coronary artery disease and 56 (32%) had a history of HTN. Fifty-three (30%) had a history of diabetes mellitus (DM) in the family; among them, 27 had diabetes and 10 were prediabetic. Fifty-six (31%) participants were admitted for >7 days following MI. Forty-eight (27%) had complications post-MI. Trend analysis showed a significant association of complications and increased hospital stay with type 2 DM (T2DM), HTN, smoking, and dyslipidemia (P < 0.05). Most of the patients 91% of T2DM, 90% of hypertensives, and 83% of patients suffering from dyslipidemia were diagnosed after they were admitted with MI. CONCLUSION: As we already know that the incidence of ischemic heart disease (IHD) is already rising in the general population, there is also an alarming rising trend of IHD in young people too. This study provides the prevalence of assorted risk factors in young MI. The rising trend of complications with an increase in risk factors studied in our group makes early diagnosis imperative for better management and prevention of complications. Increased burden of IHD in young people will lead to decreased quality of life, increased morbidity, and mortality and also have an increased economic burden for the society. This underscores the importance of building capacity of the primary health-care system for early detection of diabetes, HTN, and dyslipidemia and making people aware of unwarranted effects of smoking and alcohol consumption. Proper management and prevention of the above said risk factors would go a long way in preventing young MI as described in this study.
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