生物传感器技术的发展现状及潜在应用

I. Mani, K. Vasdev
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引用次数: 1

摘要

开发各种新型传感器,准确检测生物流体和环境样品中的生物标志物,对于疾病的早期诊断和避免污染物、有毒和生物有害物质对环境的污染具有重要意义。随着纳米材料标记荧光分子等新的生物学方法的发展,生物传感器的灵敏度限制不断提高。此外,肽阵列、适体、抗体、核苷酸和分子固定聚合物的使用有助于改进先进的生物传感器,而不是传统方法。从纳米材料、聚合物到微生物的几种生物传感器具有更广泛的潜在应用。一般来说,生物传感器已经被组织成几个类别,包含不同的传感安排,如机械、光学和电子传感器,现代生物传感器使用微纳米制造工具,作为无标签或有标签的。本文综述了生物传感器在生物医学和环境监测领域的最新发展和应用,以及生物传感器更好的检测限和更高的灵敏度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Current Developments and Potential Applications of Biosensor Technology
The development of various new kinds of sensors for the accurate detection of biomarkers in biological fluids and environmental samples are of greatest importance for the early diagnosis of diseases and to avoid the contamination of environment through pollutants, toxic and biohazardous materials. Sensitivity limits of biosensor have increased due to developments of new biological methods like tagging of fluorescence molecule with nanomaterials. Moreover, usage of peptide arrays, aptamers, antibodies, nucleotides and molecule fixed polymers, facilitate to improve advanced biosensors over conventional approaches. Several biosensors ranging from nanomaterials, polymers to microbes have broader potential applications. Generally, biosensor has been organized into several categories containing diverse sensing arrangements such as mechanical, optical and electrical transducers and modern biosensors use micro- and nanofabrication tools, as either label-free or labeled. This review provides an overview of recent developments and applications of biosensors in the fields of biomedical sciences and environmental monitoring, along with the better detection limit and improved sensitivity of the biosensors.
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