{"title":"安定不良反应;病例报告","authors":"B. Tabowei, B. Kombo, George Duke Mukoro","doi":"10.5580/2c92","DOIUrl":null,"url":null,"abstract":"Diazepam belongs to the group known as benzodiazepines tranquilizers, anxiolytics, and anti-convulsant agent. Its use as in most drugs has been associated with side effects and adverse reactions. Although a lot of therapeutic goals can be accrued to its use, the case report would highlight an unreported adverse reaction to Diazepam. A 25 years old man had an adverse reaction to diazepam after being administered as a premedication, 10mg intravenously. The observations were tachycardia, blisters all over the body, gross swelling of the right upper limb where the drug was administered, fever, diplopia, headache, as well as sudden hypotension preceded by hypertension. He was managed adequately with steroids, antihistamine, phenergan and intravenous fluid. Notwithstanding surgery for left inguinal hernia was carried-on.","PeriodicalId":22523,"journal":{"name":"The Internet Journal of Pharmacology","volume":"42 6 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2012-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Adverse Reaction To Diazepam; A Case Report\",\"authors\":\"B. Tabowei, B. Kombo, George Duke Mukoro\",\"doi\":\"10.5580/2c92\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Diazepam belongs to the group known as benzodiazepines tranquilizers, anxiolytics, and anti-convulsant agent. Its use as in most drugs has been associated with side effects and adverse reactions. Although a lot of therapeutic goals can be accrued to its use, the case report would highlight an unreported adverse reaction to Diazepam. A 25 years old man had an adverse reaction to diazepam after being administered as a premedication, 10mg intravenously. The observations were tachycardia, blisters all over the body, gross swelling of the right upper limb where the drug was administered, fever, diplopia, headache, as well as sudden hypotension preceded by hypertension. He was managed adequately with steroids, antihistamine, phenergan and intravenous fluid. Notwithstanding surgery for left inguinal hernia was carried-on.\",\"PeriodicalId\":22523,\"journal\":{\"name\":\"The Internet Journal of Pharmacology\",\"volume\":\"42 6 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2012-01-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Internet Journal of Pharmacology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5580/2c92\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Internet Journal of Pharmacology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5580/2c92","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Diazepam belongs to the group known as benzodiazepines tranquilizers, anxiolytics, and anti-convulsant agent. Its use as in most drugs has been associated with side effects and adverse reactions. Although a lot of therapeutic goals can be accrued to its use, the case report would highlight an unreported adverse reaction to Diazepam. A 25 years old man had an adverse reaction to diazepam after being administered as a premedication, 10mg intravenously. The observations were tachycardia, blisters all over the body, gross swelling of the right upper limb where the drug was administered, fever, diplopia, headache, as well as sudden hypotension preceded by hypertension. He was managed adequately with steroids, antihistamine, phenergan and intravenous fluid. Notwithstanding surgery for left inguinal hernia was carried-on.