新生儿白血病和蓝莓松饼婴儿综合征:21三体1例

IF 0.4 4区医学 Q4 MEDICAL LABORATORY TECHNOLOGY

Annales de biologie clinique Pub Date : 2023-03-15 DOI:10.1684/abc.2023.1784

Hicham Yahyaoui, Mohamed Amine Azami, Nadia El Mrimar, Abderrahim Raissi, Nadia El Idrissi Slitine, Fatiha Bennaoui, Mustapha Ait Ameur, Fadl Mrabih Rabih Maoulainine, Mohammed Chakour

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引用次数: 0

摘要

急性白血病是新生儿期罕见的疾病。它们优先发生在21三体新生儿中。它们通常表现为肝脾肿大、造血外受累和白细胞增多。蓝莓松饼婴儿综合征见于新生儿期。新生儿急性myeloïd白血病(AML)比急性淋巴细胞白血病(ALL)更为常见。尽管治疗，新生儿急性白血病预后差，总生存率低。我们报告一个病例的新生儿AML的基础上三体21揭示了蓝莓松饼婴儿综合征。

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Neonatal leukemia and Blueberry Muffin Baby Syndrome: About a case of trisomy 21

Acute leukemias are rare disease in the neonatal period. They occur preferentially in newborns with trisomy 21. They often manifest as hepatosplenomegaly, extra-hematopoietic involvement and hyperleukocytosis. Blueberry Muffin Baby syndrome is observed in the neonatal period. Neonatal acute myeloïd leukemia (AML) is more common than acute lymphoid leukemia (ALL). Despite treatment, neonatal acute leukemias have a poor prognosis with a low percentage of overall survival. We report a case of neonatal AML on a ground of trisomy 21 revealed by a Blueberry Muffin Baby syndrome.

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来源期刊

Annales de biologie clinique 医学-医学：研究与实验

CiteScore

0.80

自引率

20.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Multidisciplinary information with direct relevance to everyday practice Annales de Biologie Clinique, the official journal of the French Society of Clinical Biology (SFBC), supports biologists in areas including continuing education, laboratory accreditation and technique validation. With original articles, abstracts and accounts of everyday practice, the journal provides details of advances in knowledge, techniques and equipment, as well as a forum for discussion open to the entire community.