声音干预对癌症患者身心健康的影响:一项前瞻性随机试验。

IF 2 4区 医学 Q3 ONCOLOGY
Anna Hohneck, Rosa Meissner, Christina Reyser, Lara Heinemann, Kathrin Christians, Kirsten Merx, Simone Weingärtner, Athanasios Mavratzas, Nadine Schulte, Iris Burkholder, Wolf-Karsten Hofmann, Ralf-Dieter Hofheinz
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引用次数: 1

摘要

目的:癌症仍然是一种对发病率和死亡率以及生活质量都有重大影响的疾病。本前瞻性随机先导研究探讨声音干预对门诊癌症患者身心健康的影响。方法:为此目的使用了两种自我应用的声音干预,要么是用身体单弦主动“音乐播放”,要么是用耳机被动声音干预来听给定的音乐汇编。干预在4周的时间内进行,每晚睡前至少15分钟。在基线和4周后分别完成以下自我评估问卷:匹兹堡睡眠质量指数(PSQI)、欧洲癌症研究与治疗组织(EORTC)生活质量问卷(QLQ-C30)、疼痛和疲劳视觉模拟量表(VAS)和进展恐惧量表(FoP)。这项探索性试验的主要终点是描述患者在至少一个方面改善而没有任何其他方面恶化的比率。结果:73例患者(男性29例,女性44例)被纳入研究,随机分为主动(n = 34, 47%)和被动声音干预(n = 39, 53%)两组。中位年龄为52.0岁(21-79岁)。14名患者(19%)表示他们有音乐活动。声音干预的中位时间为26天(范围5-28天)。被动治疗组达到主要终点的患者比例更高:n = 15 (39%) vs n = 9(27%)。在VAS疲劳和QLQ-30问卷上观察到被动组的反应差异。总体而言,被动治疗组有12名患者(31%)改善了QLQ-30问卷,3名患者(9%)改善了QLQ-30问卷。此外,根据QLQ-C30,声音干预显著改善了被动组的社会功能和呼吸短促。在情感反应方面,作为FoP问卷的一个领域,被动组也注意到显著的改善。没有观察到对疼痛或睡眠质量的影响。结论:对门诊癌症患者进行为期4周的自我声音干预是可行的。通过一组5份问卷,被动的声音干预似乎更有可能对患者报告的结果产生积极影响。特别是,在社会功能和疲劳方面记录了积极的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Effects of a Sound Intervention on Physical and Emotional Well-Being in Patients with Cancer: A Prospective Randomized Trial.

Effects of a Sound Intervention on Physical and Emotional Well-Being in Patients with Cancer: A Prospective Randomized Trial.

Effects of a Sound Intervention on Physical and Emotional Well-Being in Patients with Cancer: A Prospective Randomized Trial.

Effects of a Sound Intervention on Physical and Emotional Well-Being in Patients with Cancer: A Prospective Randomized Trial.

Aim: Cancer remains a disease with a significant impact on morbidity and mortality but also on quality of life. This prospective randomized pilot study investigated the effects of a sound intervention on physical and emotional well-being in outpatients with cancer.

Methods: Two self-applied sound interventions were used for this purpose, either active "music playing" with a body monochord or passive sound intervention with headphones to listen to a given music compilation. Interventions were carried out over a period of 4 weeks for at least 15 min in the evening before bedtime. The following self-assessment questionnaires were completed both at baseline and after 4 weeks to evaluate the response: the Pittsburgh Sleep Quality Index (PSQI), the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire (QLQ-C30), Visual Analogue Scale (VAS) for pain and fatigue, and the Fear of Progression (FoP) questionnaire. Primary endpoint of this exploratory trial was to describe the rate of patients with improvement in at least one dimension without worsening of any other.

Results: 73 patients (29 male, 44 female) were included in the study and randomized to either active (n = 34, 47%) or passive sound intervention (n = 39, 53%). Median age was 52.0 years (range 21-79). Fourteen patients (19%) stated that they were musically active. The sound intervention was carried out on a median of 26 days (range 5-28). A higher percentage of patients in the passive group reached the primary endpoint: n = 15 (39%) versus n = 9 (27%). Response differences in favour of the passive group were seen with the VAS fatigue and with QLQ-30 questionnaires. Overall, an improvement in QLQ-30 questionnaire was seen in 12 patients (31%) in the passive group versus 3 patients (9%). Moreover, sound intervention significantly improved social functioning and shortness of breath in the passive group according to QLQ-C30. Significant improvements were also noticed in the passive group in terms of affective reactions as a domain of the FoP questionnaire. No effects on pain or sleep quality could be observed.

Conclusion: A 4-week self-administered sound intervention was feasible in outpatients suffering from cancer. Using a panel of 5 questionnaires, passive sound interventions appeared to be more likely to positively influence patient-reported outcomes. In particular, a positive impact was documented in social functioning and fatigue.

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来源期刊
CiteScore
3.20
自引率
0.00%
发文量
84
期刊介绍: With the first issue in 2014, the journal ''Onkologie'' has changed its title to ''Oncology Research and Treatment''. By this change, publisher and editor set the scene for the further development of this interdisciplinary journal. The English title makes it clear that the articles are published in English – a logical step for the journal, which is listed in all relevant international databases. For excellent manuscripts, a ''Fast Track'' was introduced: The review is carried out within 2 weeks; after acceptance the papers are published online within 14 days and immediately released as ''Editor’s Choice'' to provide the authors with maximum visibility of their results. Interesting case reports are published in the section ''Novel Insights from Clinical Practice'' which clearly highlights the scientific advances which the report presents.
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