鼻窦道恶性肿瘤的最新进展：诊断方式的进展。

IF 3.7 3区医学 Q2 MEDICAL LABORATORY TECHNOLOGY

Archives of pathology & laboratory medicine Pub Date : 2024-10-01 DOI:10.5858/arpa.2022-0447-RA

Maria A Gubbiotti, Virginia LiVolsi, Kathleen T Montone

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引用次数: 0

摘要

背景鼻窦道恶性肿瘤是一种罕见的癌症，其形态经常发生重叠。鉴于许多此类肿瘤具有相似的组织学特征，它们常常给执业病理学家带来诊断上的挑战：利用组织学线索、免疫组化图谱和分子检测提供一种简化算法，以帮助诊断这些病变：数据来源包括世界卫生组织肿瘤分类、文献综述和机构经验：尽管许多鼻窦道恶性肿瘤显示出相似的组织学特征，但不同的免疫组化和分子图谱有助于区分差异，从而为病理学家的诊断提供便利。

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Update on Sinonasal Tract Malignancies: Advances in Diagnostic Modalities.

Context.—: Sinonasal tract malignancies are rare cancers with frequent morphologic overlap. Given the similar histologic profiles seen in many of these entities, they often present a diagnostic challenge to the practicing pathologist.

Objective.—: To provide a streamlined algorithm using histologic clues, immunohistochemical profiles, and molecular assays to aid in diagnosis of these lesions.

Data sources.—: Sources were the World Health Organization Tumor Classification, literature review, and institutional experience.

Conclusions.—: Although many sinonasal tract malignancies show similar histology, distinct immunohistochemical and molecular profiles can help parse out differences, thereby facilitating diagnosis for the pathologist.

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来源期刊

Archives of pathology & laboratory medicine 医学-病理学

CiteScore

9.20

自引率

2.20%

发文量

369

审稿时长

3-8 weeks

期刊介绍： Welcome to the website of the Archives of Pathology & Laboratory Medicine (APLM). This monthly, peer-reviewed journal of the College of American Pathologists offers global reach and highest measured readership among pathology journals. Published since 1926, ARCHIVES was voted in 2009 the only pathology journal among the top 100 most influential journals of the past 100 years by the BioMedical and Life Sciences Division of the Special Libraries Association. Online access to the full-text and PDF files of APLM articles is free.