Burcu Kemer Atik, Cigdem Altan, Seren Pehlivanoglu, Sibel Ahmet
{"title":"增殖性糖尿病视网膜病变全视网膜光凝术后早期水斑和眼压的变化。","authors":"Burcu Kemer Atik, Cigdem Altan, Seren Pehlivanoglu, Sibel Ahmet","doi":"10.14744/bej.2022.13471","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>The aim of the study was to investigate the effect of panretinal photocoagulation (PRP) on aqueous flare and intraocular pressure (IOP) in the early period.</p><p><strong>Methods: </strong>Eighty-eight eyes of 44 patients were included in the study. The patients underwent a full ophthalmologic examination including the best corrected visual acuity, IOP measured by Goldmann applanation tonometry, biomicroscopy, and dilated fundus examination before PRP. Aqueous flare values were measured by the laser flare meter. Aqueous flare and IOP values were repeated in both eyes at the 1<sup>st</sup> and 24<sup>th</sup> h after PRP. The eyes of the patients who underwent PRP were included in the study as the study group, and the other eyes as the control group.</p><p><strong>Results: </strong>In eyes treated with PRP, 1<sup>st</sup> h (19.44 pc/ms) and 24<sup>th</sup> h (18.53 pc/ms) aqueous flare values were statistically higher than before PRP (16.66 pc/ms) (p<0.05). In the study eyes which were similar to the control eyes before PRP, the aqueous flare was higher at the 1<sup>st</sup> and 24<sup>th</sup> h after PRP compared to control eyes (p<0.05). The mean IOP at the 1<sup>st</sup> h (18.69 mmHg) after PRP in study eyes was higher than both pre-PRP (16.25 mmHg) and post-PRP 24<sup>th</sup> h (16.12 mmHg) IOP values (p<0.001). At the same time, the IOP value at the 1<sup>st</sup> h after PRP was higher than the control eyes (p=0.001). No correlation was observed between aqueous flare and IOP values.</p><p><strong>Conclusion: </strong>An increase in aqueous flare and IOP values was observed after PRP. Besides, the increase in both values starts even in the 1<sup>st</sup> h, and the values at 1<sup>st</sup> h are the highest values. At the 24<sup>th</sup> h, while IOP values return to baseline, aqueous flare values are still high. In patients who may develop severe intraocular inflammation or cannot tolerate increased IOP (such as previous uveitis, neovascular glaucoma, or severe glaucoma), control should be performed at the 1<sup>st</sup> h after PRP to prevent irreversible complications. Furthermore, the progression that may develop in diabetic retinopathy due to increased inflammation should also be kept in mind.</p>","PeriodicalId":8740,"journal":{"name":"Beyoglu Eye Journal","volume":"8 1","pages":"26-31"},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/53/e9/BEJ-8-26.PMC9993421.pdf","citationCount":"0","resultStr":"{\"title\":\"Aqueous Flare and Intraocular Pressure in the Early Period Following Panretinal Photocoagulation in Patient with Proliferative Diabetic Retinopathy.\",\"authors\":\"Burcu Kemer Atik, Cigdem Altan, Seren Pehlivanoglu, Sibel Ahmet\",\"doi\":\"10.14744/bej.2022.13471\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>The aim of the study was to investigate the effect of panretinal photocoagulation (PRP) on aqueous flare and intraocular pressure (IOP) in the early period.</p><p><strong>Methods: </strong>Eighty-eight eyes of 44 patients were included in the study. The patients underwent a full ophthalmologic examination including the best corrected visual acuity, IOP measured by Goldmann applanation tonometry, biomicroscopy, and dilated fundus examination before PRP. Aqueous flare values were measured by the laser flare meter. Aqueous flare and IOP values were repeated in both eyes at the 1<sup>st</sup> and 24<sup>th</sup> h after PRP. The eyes of the patients who underwent PRP were included in the study as the study group, and the other eyes as the control group.</p><p><strong>Results: </strong>In eyes treated with PRP, 1<sup>st</sup> h (19.44 pc/ms) and 24<sup>th</sup> h (18.53 pc/ms) aqueous flare values were statistically higher than before PRP (16.66 pc/ms) (p<0.05). In the study eyes which were similar to the control eyes before PRP, the aqueous flare was higher at the 1<sup>st</sup> and 24<sup>th</sup> h after PRP compared to control eyes (p<0.05). The mean IOP at the 1<sup>st</sup> h (18.69 mmHg) after PRP in study eyes was higher than both pre-PRP (16.25 mmHg) and post-PRP 24<sup>th</sup> h (16.12 mmHg) IOP values (p<0.001). At the same time, the IOP value at the 1<sup>st</sup> h after PRP was higher than the control eyes (p=0.001). No correlation was observed between aqueous flare and IOP values.</p><p><strong>Conclusion: </strong>An increase in aqueous flare and IOP values was observed after PRP. Besides, the increase in both values starts even in the 1<sup>st</sup> h, and the values at 1<sup>st</sup> h are the highest values. At the 24<sup>th</sup> h, while IOP values return to baseline, aqueous flare values are still high. In patients who may develop severe intraocular inflammation or cannot tolerate increased IOP (such as previous uveitis, neovascular glaucoma, or severe glaucoma), control should be performed at the 1<sup>st</sup> h after PRP to prevent irreversible complications. Furthermore, the progression that may develop in diabetic retinopathy due to increased inflammation should also be kept in mind.</p>\",\"PeriodicalId\":8740,\"journal\":{\"name\":\"Beyoglu Eye Journal\",\"volume\":\"8 1\",\"pages\":\"26-31\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/53/e9/BEJ-8-26.PMC9993421.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Beyoglu Eye Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.14744/bej.2022.13471\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Beyoglu Eye Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14744/bej.2022.13471","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
目的:探讨全视网膜光凝术(PRP)对早期水性耀斑和眼内压(IOP)的影响。方法:选取44例患者88只眼作为研究对象。患者在PRP前接受了全面的眼科检查，包括最佳矫正视力，Goldmann眼压计测量的IOP，生物显微镜和眼底扩张检查。用激光耀斑计测量了水溶液的耀斑值。在PRP后第1和24 h重复两眼的水光斑和IOP值。将行PRP的患者的眼睛作为研究组，另一只眼睛作为对照组。结果:PRP治疗后第1 h (19.44 pc/ms)和第24 h (18.53 pc/ms)水光斑值均高于PRP治疗前(16.66 pc/ms)， PRP治疗后第24 h (18.69 mmHg)眼压值均高于PRP治疗前(16.25 mmHg)和PRP治疗后第24 h (16.12 mmHg)眼压值(PRP治疗后pst h均高于对照组(p=0.001)。在水耀斑和IOP值之间没有观察到相关性。结论:PRP术后水光斑和IOP值均有升高。此外，这两个值的增加甚至从第一个h开始，并且第一个h的值是最高的。在第24小时，虽然IOP值恢复到基线，但水内耀斑值仍然很高。对于可能出现严重眼内炎症或不能耐受IOP升高的患者(如既往的葡萄膜炎、新生血管性青光眼或严重青光眼)，应在PRP后1小时进行控制，以防止不可逆并发症的发生。此外，糖尿病视网膜病变可能因炎症增加而发展的进程也应牢记在心。
Aqueous Flare and Intraocular Pressure in the Early Period Following Panretinal Photocoagulation in Patient with Proliferative Diabetic Retinopathy.
Objectives: The aim of the study was to investigate the effect of panretinal photocoagulation (PRP) on aqueous flare and intraocular pressure (IOP) in the early period.
Methods: Eighty-eight eyes of 44 patients were included in the study. The patients underwent a full ophthalmologic examination including the best corrected visual acuity, IOP measured by Goldmann applanation tonometry, biomicroscopy, and dilated fundus examination before PRP. Aqueous flare values were measured by the laser flare meter. Aqueous flare and IOP values were repeated in both eyes at the 1st and 24th h after PRP. The eyes of the patients who underwent PRP were included in the study as the study group, and the other eyes as the control group.
Results: In eyes treated with PRP, 1st h (19.44 pc/ms) and 24th h (18.53 pc/ms) aqueous flare values were statistically higher than before PRP (16.66 pc/ms) (p<0.05). In the study eyes which were similar to the control eyes before PRP, the aqueous flare was higher at the 1st and 24th h after PRP compared to control eyes (p<0.05). The mean IOP at the 1st h (18.69 mmHg) after PRP in study eyes was higher than both pre-PRP (16.25 mmHg) and post-PRP 24th h (16.12 mmHg) IOP values (p<0.001). At the same time, the IOP value at the 1st h after PRP was higher than the control eyes (p=0.001). No correlation was observed between aqueous flare and IOP values.
Conclusion: An increase in aqueous flare and IOP values was observed after PRP. Besides, the increase in both values starts even in the 1st h, and the values at 1st h are the highest values. At the 24th h, while IOP values return to baseline, aqueous flare values are still high. In patients who may develop severe intraocular inflammation or cannot tolerate increased IOP (such as previous uveitis, neovascular glaucoma, or severe glaucoma), control should be performed at the 1st h after PRP to prevent irreversible complications. Furthermore, the progression that may develop in diabetic retinopathy due to increased inflammation should also be kept in mind.
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