洞察成人柔毛细胞星形细胞瘤的特点和手术切除可能性:三级中心的经验。

Q1 Medicine
CNS Oncology Pub Date : 2022-04-06 DOI:10.2217/cns-2021-0014
Baha'eddin A Muhsen, Abdelmajid I Aljariri, Maher Elayyan, Hawazen Hirbawi, Mahmoud A Masri
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引用次数: 0

摘要

目的:成人朝天性星形细胞瘤是一种罕见肿瘤。我们旨在帮助了解其临床过程和预后。患者和方法:我们在数据库中搜索了18岁以上、经病理证实患有梨状细胞星形细胞瘤的患者。对患者的临床数据进行了分析。结果共发现 15 名患者。确诊时的中位年龄为25岁(18-56岁)。47%的肿瘤位于幕上。40%的患者实现了全切和近全切,47%的患者实现了次全切。中位随访时间为11个月(1-76个月),其中1例(7%)复发,无死亡病例。结论与儿科相比,嗜酸性粒细胞星形细胞瘤在成人中的表现有所不同。它往往发生在手术难度较大的区域,切除范围可能有限。在可行的情况下,应将全切除作为主要治疗手段。存活率较高,复发率较低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Insight about the characteristics and surgical resectability of adult pilocytic astrocytoma: tertiary center experience.

Aim: Adult pilocytic astrocytoma is a rare tumor. We aim to contribute to understanding its clinical course and prognosis. Patients & methods: We searched our database for patients older than 18 years with pathology-proven pilocytic astrocytoma. Patients' clinical data were analyzed. Results: Fifteen patients were identified. The median age at diagnosis was 25 years (range: 18-56). Tumors were supratentorial in 47%. Gross-total and near-total resections were achieved in 40%, and sub-total resection in 47%. One (7%) recurrence and no mortality were encountered during a median follow-up of 11 months (range: 1-76). Conclusion: Pilocytic astrocytoma behaves differently in adults compared with pediatrics. It tends to arise in surgically challenging areas where the extent of resection may be limited. Total resection should be the main therapy whenever feasible. The survival rates are good, and recurrence is low.

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来源期刊
CNS Oncology
CNS Oncology Medicine-Neurology (clinical)
CiteScore
3.80
自引率
0.00%
发文量
12
审稿时长
13 weeks
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