{"title":"紫锥菊草和紫锥菊片中酚羧酸含量的高效液相色谱法研究","authors":"Anastasia Yuryevna Romarchuk","doi":"10.33920/med-13-2204-02","DOIUrl":null,"url":null,"abstract":"Echinacea herb and preparations based on it have the immunomodulatory and anti-inflammatory properties necessary for today, which is due to the presence of phenolcarboxylic acids in their composition. At the moment, the quantitative determination of phenolcarboxylic acids in echinacea tablets requires time-consuming sample preparation and determination by a spectrophotometric method that does not have sufficient specificity. In this regard, it is proposed to standardize the quantitative determination of phenolcarboxylic acids in echinacea tablets by HPLC, which will effectively separate the components of the mixture to study its composition, establish the dominant of chicory acid in the water-ethanol extract, and also reduce the time spent on analysis.","PeriodicalId":12259,"journal":{"name":"Farmacevticheskoe delo i tehnologija lekarstv (Pharmacy and Pharmaceutical Technology)","volume":"6 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Study of phenol carboxylic acids in echinacea grass and echinacea tablets in order to develop a technique for their quantitative determination using high-performance liquid chromatography (HPLC)\",\"authors\":\"Anastasia Yuryevna Romarchuk\",\"doi\":\"10.33920/med-13-2204-02\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Echinacea herb and preparations based on it have the immunomodulatory and anti-inflammatory properties necessary for today, which is due to the presence of phenolcarboxylic acids in their composition. At the moment, the quantitative determination of phenolcarboxylic acids in echinacea tablets requires time-consuming sample preparation and determination by a spectrophotometric method that does not have sufficient specificity. In this regard, it is proposed to standardize the quantitative determination of phenolcarboxylic acids in echinacea tablets by HPLC, which will effectively separate the components of the mixture to study its composition, establish the dominant of chicory acid in the water-ethanol extract, and also reduce the time spent on analysis.\",\"PeriodicalId\":12259,\"journal\":{\"name\":\"Farmacevticheskoe delo i tehnologija lekarstv (Pharmacy and Pharmaceutical Technology)\",\"volume\":\"6 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-03-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Farmacevticheskoe delo i tehnologija lekarstv (Pharmacy and Pharmaceutical Technology)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.33920/med-13-2204-02\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Farmacevticheskoe delo i tehnologija lekarstv (Pharmacy and Pharmaceutical Technology)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33920/med-13-2204-02","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Study of phenol carboxylic acids in echinacea grass and echinacea tablets in order to develop a technique for their quantitative determination using high-performance liquid chromatography (HPLC)
Echinacea herb and preparations based on it have the immunomodulatory and anti-inflammatory properties necessary for today, which is due to the presence of phenolcarboxylic acids in their composition. At the moment, the quantitative determination of phenolcarboxylic acids in echinacea tablets requires time-consuming sample preparation and determination by a spectrophotometric method that does not have sufficient specificity. In this regard, it is proposed to standardize the quantitative determination of phenolcarboxylic acids in echinacea tablets by HPLC, which will effectively separate the components of the mixture to study its composition, establish the dominant of chicory acid in the water-ethanol extract, and also reduce the time spent on analysis.