新型冠状病毒感染后患者症状特征及康复影响因素分析

Norihiro Matsuoka, Takuo Mizutani, Koji Kawakami
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摘要

背景:本研究旨在探讨影响2019冠状病毒病(COVID-19)后症状改善的因素。方法:对我院120例新冠肺炎后症状门诊患者(男44例,女76例)的生物标志物及症状状况进行调查。本研究为回顾性分析,因此我们只分析那些能够跟踪症状进展12周的患者的症状过程。我们分析了包括水合乙酸锌摄入量在内的数据。结果:12周后的主要症状依次为味觉障碍、嗅觉障碍、脱发、疲劳。8周后,水合乙酸锌治疗组的疲劳症状均有改善,与未治疗组比较差异有统计学意义(P = 0.030)。即使在12周后也观察到类似的趋势,尽管没有显著差异(P = 0.060)。在脱发方面,与未治疗组相比,用醋酸锌水合物治疗组在4、8和12周后表现出显著的改善(P = 0.002, P = 0.002和P = 0.006)。结论:水合乙酸锌可改善COVID-19感染后的疲劳和脱发症状。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Symptom Profile of Patients With Post-COVID-19 Conditions and Influencing Factors for Recovery.

Symptom Profile of Patients With Post-COVID-19 Conditions and Influencing Factors for Recovery.

Symptom Profile of Patients With Post-COVID-19 Conditions and Influencing Factors for Recovery.

Background: The aim of the study was to examine the factors that influence the improvement of post-coronavirus disease 2019 (COVID-19) symptoms.

Methods: We investigated the biomarkers and post-COVID-19 symptoms status of 120 post-COVID-19 symptomatic outpatients (44 males and 76 females) visiting our hospital. This study was a retrospective analysis, so we analyzed the course of symptoms only for those who could follow the progress of the symptoms for 12 weeks. We analyzed the data including the intake of zinc acetate hydrate.

Results: The main symptoms that remained after 12 weeks were, in descending order: taste disorder, olfactory disorder, hair loss, and fatigue. Fatigue was improved in all cases treated with zinc acetate hydrate 8 weeks later, exhibiting a significant difference from the untreated group (P = 0.030). The similar trend was observed even 12 weeks later, although there was no significant difference (P = 0.060). With respect to hair loss, the group treated with zinc acetate hydrate showed significant improvements 4, 8, and 12 weeks later, compared with the untreated group (P = 0.002, P = 0.002, and P = 0.006).

Conclusion: Zinc acetate hydrate may improve fatigue and hair loss as symptoms after contracting COVID-19.

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